Publications by authors named "Parviz Khajehdehi"

Introduction: The global prevalence of chronic kidney disease (CKD) is increasing consistently. Progression of CKD to end-stage renal disease could be slowed down by early detection and treatment, yet CKD and its risk factors have been poorly studied in many countries. This study investigated the CKD prevalence and its contributing risk factors in adult population of Southern Iran.

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Aim. The prevalence of chronic kidney disease (CKD) as a serious public health problem is growing in the elderly. This study aimed to assess CKD prevalence and its related risk factors in elderly population of Fars province.

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Context: Turmeric (Curcuma longa) is a wild plant of the ginger family native to tropical South Asia.

Evidence Acquisitions: Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science have been searched.

Results: Emerging evidence indicate that turmeric/curcumin inhibits cytokines and TGF-β production.

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Objective: Despite highly expensive treatments, lupus nephritis remains a major cause of morbidity and mortality in patients with relapsing or refractory lupus nephritis. Meanwhile, experimental studies indicate that curcumin attenuates both the binding of autoantibodies from systemic lupus erythematosus patients to their cognate antigens and also the inflammatory responses of tumor necrosis factor-alpha-stimulated human endothelial cells. Therefore, in this study we investigated effect(s) of oral curcumin supplementation on patients suffering from relapsing or refractory lupus nephritis.

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Objective: End-stage renal disease (ESRD) due to type 2 diabetic nephropathy is a very common condition which is increasing in prevalence, and is associated with high global levels of mortality and morbidity. Both proteinuria and transforming growth factor-β (TGF-β) may contribute to the development of ESRD in patients with diabetic nephropathy. Experimental studies indicate that turmeric improves diabetic nephropathy by suppressing TGF-β.

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Although it is well known that diabetics are at a higher risk of contrast-induced acute kidney injury (CI-AKI) than nondiabetic patients, the reason for this discrepancy is not well known. Thus, in this study, we compared the predisposing factors for CI-AKI between patients with and without diabetes. We prospectively studied 290 consecutive in-hospital patients including 88 diabetics undergoing coronary angiography or a percutaneous coronary intervention in Kowsar hospital, and we compared risk factors for CI-AKI between diabetic and nondiabetic patients.

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Chronic renal failure (CRF) is characterized by impaired renal function, which is progressive and irreversible. This study was carried out to investigate the status and causes of CRF in HD patients in Fars Province, Iran. In this cross-sectional study, HD patients were evaluated in Fars province.

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Article Synopsis
  • The study focuses on the effectiveness of bicarbonate infusion compared to normal saline and its combination with acetazolamide in preventing contrast-induced nephropathy (CIN) during coronary procedures.
  • Patients were randomly assigned to receive either normal saline, normal saline with acetazolamide, or bicarbonate before undergoing angiography, with renal function assessed using RIFLE criteria for acute kidney injury (AKI).
  • Findings indicate that bicarbonate and acetazolamide significantly lower the AKI risk associated with CIN compared to normal saline, while also highlighting the need for monitoring potassium levels during bicarbonate treatment.
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Objective: To more clearly elucidate the conflicting results that have been obtained after oral calcitriol pulse therapy on lipid, glucose, and calcium levels in hemodialysis (HD) patients, and to determine safety of oral calcitriol pulse therapy in a combination with calcium carbonate.

Design: A randomized, crossover, placebo-controlled study.

Setting: HD centers in 3 teaching university hospitals.

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