Reduction in protein absorption on ophthalmic lenses by PEGDA bulk modification of silicone acrylate-based formulation.

The absorption of protein and formation of biofilms on the surface of ophthalmic lenses is one of the factors that destroy their useful performance by causing severe visual impairment, inflammation, dryness and ultimate eye discomfort. Therefore, eye lenses need to be resilient to protein absorption, which is one of the opacity factors in minimizing protein absorption on the lenses. The purpose of this study was to investigate and reduce sediment biotransformation on the surface of the semi-hardened lens based on acrylate by bulk-free radical polymerization method.

Polyurethane synthesis for vascular application.

Three polyurethane formulations were prepared on the basis of siloxane; two formulations contained 1% and 3% of a hydroxyl functionalized polyhedral oligomeric silsesquioxane [POSS (ROH)] nano-particles (as a co-chain extender) and one was without nano-particle. Structures of the polyurethanes were characterized by FTIR and SEM. The effect of POSS nano-particles on properties of the synthesized PUs was examined for vascular applications by tensile test, contact angle, SEM, AFM and endothelial cells viability evaluation.