Lineage and sublineage analysis of human papillomavirus type 58 in iranian women.

Background: Variant analysis of distinct HPV types is important from different aspects including epidemiology, pathogenicity, and evolution.

Methods: For this reason, the full sequence of the E6 and E7 genes of HPV 58 was examined in 130 HPV 58-infected cervical samples using PCR and sequencing.

Results: Our results revealed that three lineages A, B, and D were found in this study; among which the B lineage was more common (91.

Variant analysis of human papillomavirus type 52 in Iranian women during 2018-2020: A case-control study.

Background And Aims: Knowing the regional variants of distinct human papillomavirus (HPV) types is valuable as it can be beneficial for studying their epidemiology, pathogenicity, and evolution. For this reason, the sequence variations of the E6 gene of HPV 52 were investigated among women with normal cervical cytology and premalignant/malignant cervical samples.

Methods: Sixty-four HPV 52-positive samples were analyzed using semi-nested PCR and sequencing.

Lineage and sublineage analysis of human papillomavirus type 56 in cervical samples of Iranian women.

Understanding the regional lineages and sublineages of human papillomavirus type 56 (HPV 56) would be of great importance for further evolutionary, epidemiological, and biological investigations. To identify the distribution of lineages and sublineages of HPV 56 in Iran, the sequence variations of the E6 gene were analyzed in normal, premalignant, and malignant samples obtained from the cervix. In total, 58 HPV 56-positive samples were investigated by nested-PCR and followed by bidirectional direct nucleotide sequencing analysis.