Exploring oral candidiasis among cancer patients undergoing chemotherapy in eastern Iran.

Background And Objectives: Understanding the epidemiology of species among cancer patients is crucial for preventing invasive infections. This study aimed to identify species and assess risk factors among cancer patients receiving chemotherapy in Birjand, eastern Iran.

Materials And Methods: The samples were obtained from the oral cavity of 140 patients and the initial identification of species was carried out through fungal cultures.

Antimicrobial Peptides as a Promising Therapeutic Strategy for Neisseria Infections.

Antibiotic resistance is already widespread in the world, and it has become a great health problem. Therefore, comprehensive efforts are needed to minimize the resistance. The exploration of alternative therapies may offer a more targeted approach with less susceptibility to resistance.

Levofloxacin-based therapy as an efficient alternative for eradicating Helicobacter pylori infection in Iran: a systematic review and meta-analysis.

Objectives: Despite excessive resistance of Helicobacter pylori to clarithromycin among the Iranian population, clarithromycin-based therapy is still prescribed in Iran. Recent studies have shown high rates of H. pylori eradication in patients treated with levofloxacin.

High prevalence of multidrug-resistant non-fermentative Gram-negative bacilli harboring and metallo-beta-lactamase genes in Birjand, south-east Iran.

Background And Objectives: Non-fermentative Gram-negative Bacilli (NFGNB) is known as a major cause of healthcare-associated infections with high levels of antibiotic resistance. The aim of this study was to investigate the antibiotic resistance profiles and molecular characteristics of metallo-beta-lactamase (MBL)-producing NFGNB.

Materials And Methods: In this cross-sectional study, the antibiotic resistance profile of 122 clinical NFGNB isolates was determined by the Kirby-Bauer disk diffusion and microdilution broth methods.

In vitro and in vivo toxicity and antibacterial efficacy of melittin against clinical extensively drug-resistant bacteria.

Background: Melittin is one of the most studied antimicrobial peptides, and several in vitro experiments have demonstrated its antibacterial efficacy. However, there is evidence showing melittin has non-promising effects such as cytotoxicity and hemolysis. Therefore, concerns about unwanted collateral toxicity of melittin lie ahead in the path toward its clinical development.

First Report of Prevalence of CTX-M-15-Producing Escherichia coli O25b/ST131 from Iran.

The emergence of Escherichia coli sequence type 131 (ST131) as a multidrug-resistant and virulent pathogen represents a major challenge to public health globally. Recently, the O25b/ST131 E. coli producing CTX-M-15 with high virulence potential has been reported worldwide, but has received little attention in Iran.