Publications by authors named "Parusov V"

White rat experiments were made to study healing of cutaneous wounds in acute and chronic alcohol-substitute intoxications. Physico-morphological, bacterioscopic and cytochemical examinations showed that oral introduction of ethanol, methanol and their mixture inhibited healing of the wounds due to suppuration.

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Peculiar ultrastructural features allowed the authors to reveal M. Homminis corpuscles in placental tissues of women with genital mycoplasmosis. Mycoplasma was found in the amniotic epithelium, chorionic plate, in the lumen of villous capillaries, this showing possible hematogenic way of the infection from mother to fetus.

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Modelling of experimental influenza infection was performed in an aerosol apparatus the main element of which was a glove box made of organic glass. Mice were infected by inhalation of a highly dispersed aerosol of influenza A2/Victoria/72 virus adapted to the mouse lungs. The aerosol was produced by means of a pneumatic atomizer.

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Toxic pulmonary edema during influenza developed 3 hours after infection of mice with concentrated influenza viruses adapted to lung tissue. The toxic viral action is expressed in filling the alveoli with fluid exudate, by stasis in the pulmonary vessels, by eosinophilic necrosis of the epithelium in the bronchioles, and also by destruction of cells of the cortical layer of the thymus. The elaborated model aids in the understanding of malignant forms of influenza infection in man resulting in death.

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Morphogenesis of cytoplasmic inclusions was studied in experimental influenza infection in white mice. It was shown that cytoplasmic inclusions in influenza represented foci of partial degeneration and necrosis of the cytoplasm, the developmental phases of which are similar to phases of formation by means of autolysis. The disintegration of the content of inclusions in the epithelial cells of the bronchi was accompanied by accumulation in their zone of enzyme-containing structures of the type of tegmented vesicles.

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Study of five M. pneumoniae strains by the intensity of hemolysis and hemadsorption demonstrated no definite differences between them. Experiments on Cricetus auratus W.

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The pathomorphological and virological study of peculiar features of parainfluenza infection caused by intranasal, aerosol and oral administration of the virus was carried out. The most marked lesions in the respiratory tract were observed in hamsters infected by the intranasal route, whereas with other routes of infection the intensity of lesions was minimal. Such differences in the pathomorphological manifestations of the process are most probably due to uneven distribution of the virus in the respiratory organs and to peculiar features of the immunological response of the animals.

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