Comparative evaluation of dexmedetomidine and midazolam-ketamine combination as sedative agents in pediatric dentistry: A double-blinded randomized controlled trial.

Background: Pharmacological methods have been used as an adjunct to enhance child cooperativeness and facilitate dental treatment.

Objective: Purpose of this study was to evaluate and compare the effect of sedation by intranasal dexmedetomidine and oral combination drug midazolam-ketamine in a group of children with uncooperative behavior requiring dental treatment.

Materials And Methods: This was a prospective, randomized, double-blind study that included patients 3-9 years old with American Society of Anesthesiologists-I status.