Indocyanine green angiography reveals choroidal hypoperfusion in subacute sclerosing panencephalitis (SSPE).

We report the choroidal findings on indocyanine green angiography (ICGA) in two cases of subacute sclerosing panencephalitis (SSPE). The two immunocompetent patients (31-year-old and 30-year-old Asian Indian males) presented with acute-onset rapidly progressing vision loss with findings of necrotizing retinitis involving the central macula. Both patients tested negative for serological evidence of herpes or varicella, and toxoplasma antibodies.

Clinical Profile and Ocular Morbidities in Patients with Both Diabetic Retinopathy and Uveitis.

Purpose: To describe the clinical profile and complications of diabetic retinopathy (DR) and uveitis in patients with coexisting conditions and to derive associations based on site of primary inflammation, stage of DR, and complications of each.

Design: Single-center, cross-sectional observational study.

Participants: Sixty-six patients with coexisting DR and uveitis.

Paenibacillus lautus: A new foe in endogenous endophthalmitis.

Purpose: To discuss the diagnosis and management of a rare case of endogenous endophthalmitis (EE) caused by Paenibacillus lautus mimicking granulomatous uveitis in a child, highlighting the use of 16S rRNA gene amplicon sequencing as an accurate method to identify rare pathogens.

Method: A retrospective chart review of the clinical presentation, microbiologic workup-including microscopy, culture, antibiotic susceptibility, and polymerase chain reaction for pathogen DNA of clinical samples-and the clinical management of the case were recorded.

Result: A 13-year-old boy presented with decreased vision in the right eye for one month.

A case of granulomatosis with polyangiitis-associated scleritis presenting as conjunctivitis.

A 42-year-old male presented initially with conjunctivitis and was treated with topical medical medications without any improvement. He developed ocular pain subsequently and further examination revealed lid edema, conjunctival hyperemia with chemosis, matting of lashes with yellowish discharge, and deeper episcleral congestion which did not blanch with topical vasoconstrictor. Subsequent laboratory investigation revealed positive cytoplasmic-antineutrophil cytoplasmic antibody (Anti-PR 3 antibody).

A COVID-19 perspective of multiple evanescent white dot syndrome (MEWDS).

Multiple evanescent white dot syndrome (MEWDS) is a rare form of posterior uveitis characterized by involvement in the posterior pole and mid-periphery. A viral etiology that provokes an immune-mediated response has been hypothesized to be the inciting factor of the pathology. Recently, there has been an increase in the literature regarding new-onset uveitis and reactivation of previously diagnosed cases of uveitis following COVID-19 vaccinations.

Role of eccentric viewing training with microperimeter for low vision rehabilitation in multifocal choroiditis: Case report.

A 21-year-old student with healed multifocal choroiditis involving the macula presented with difficulty in seeing distance and reading her college books. Based on microperimetr'y, the location of her preferred retinal locus and the position of new trained retinal locus (TRL) were identified. With multiple sessions of biofeedback training, her mean retinal sensitivity improved from 4.

A case of non-Hodgkin lymphoma diagnosed after 35-month of initial presentation as recurrent vitritis with multiple negative biopsies.

To report a case of non-Hodgkin lymphoma (NHL) that was diagnosed 35-month of initial ocular manifestation. Retrospective chart review. A 53-year-old male presented with painless diminution of vision in both eyes.

Clinical profile, treatment, and visual outcome of scleritis: A single ophthalmologist experience.

Purpose: The purpose of this study was to analyze the clinical profile of patients with scleritis managed by a single ophthalmologist in a tertiary eye care center.

Methods: This was a retrospective analysis of 107 eyes of 96 patients with scleritis from January 2007 to December 2018.

Results: Female predominance (68%) with a relatively young-onset (46 ± 14 years) of scleritis was observed.

Clinical spectrum of HLA-B27-associated ocular inflammation.

Introduction: HLA-B27-associated anterior uveitis is the most common identifiable cause of anterior uveitis in adults worldwide. It is associated with significant ocular morbidity in young patients due to its typically recurrent attacks of inflammation and vision-threatening ocular complications.

Materials And Methods: This review was compiled using articles identified by searching on PubMed with all relevant keywords such as HLA B27, HLA B27 uveitis, spondyloarthritis, Ankylosing spondylitis, HLA B27 systemic associations.

A case series of presumed fungal endogenous endophthalmitis in post COVID-19 patients.

The novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2, has challenged the medical community. Several ocular manifestations secondary to COVID-19 have been documented. Prolonged hospitalization exposes the patient to various multiresistant bacteria making them prone to various secondary infections.

Papillophlebitis as an initial presentation of Eales' disease.

Eales' disease (ED), which is an idiopathic obliterative vasculitis, is a diagnosis of exclusion. The optic nerve involvement in ED is not very common. We report a case of ED in a 36-year-old male who initially presented as papillephlebitis.

scleritis initially presenting as idiopathic diffuse anterior scleritis.

remains the most common cause of bacterial scleritis. This report illustrates an unusual presentation of scleritis, which initially presented as diffuse anterior scleritis with anterior uveitis. The detailed laboratory work-up of the patient was negative, and the initiation of high-dose oral corticosteroid therapy led to further deterioration of clinical condition, with the appearance of a yellowish-white nodule within 3 days.

Anterior chamber migration of a sustained-release dexamethasone intravitreal implant: A case report and review of literature.

The purpose of the study was to report a case of migration of a dexamethasone intravitreal implant (Ozurdex) into anterior chamber and review the literature pertaining to the anterior chamber migration of implant. Clinical data were collected from a patient, in whom a dexamethasone intravitreal implant migrated to anterior chamber. A review of literature was conducted to analyze additional reports.

Serial swept-source optical coherence tomography: Tale of a choroidal tuberculoma.

Choroidal tuberculoma is a solitary elevated choroidal mass-like lesion regarded often characteristic of intraocular tuberculosis. Serial swept-source optical coherence tomography (SS-OCT) is a very important tool in monitoring the course of choroidal tuberculoma and allows in early detection of complications such as choroidal neovascular membrane (CNVM). We describe a 26-year-old young Indian female, who presented with a solitary choroidal mass lesion in the left eye.

Clinical profile of uveitis patients developing central serous chorioretinopathy: An experience at a tertiary eye care center in India.

Purpose: To evaluate clinical profile of patients with uveitis who developed central serous chorioretinopathy (CSC).

Methods: Retrospective case series of consecutive patients of uveitis with CSC managed at a tertiary eye care center in India between 1994 and 2014. The data about clinical features, investigations, treatment, and outcomes were obtained from their medical records.