Publications by authors named "Parthasarathy Muralidharan"

India has a high burden of hypertension (HTN), which is often poorly controlled, leading to hypertension-mediated organ damage (HMOD). In the management of HTN, angiotensin receptor blockers (ARBs) assume prime importance, being first-line agents for most patient subgroups. Olmesartan is a highly efficacious ARB that demonstrates sustained blood pressure (BP) reduction over 24 hours.

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India has a high burden of patients with diabetes mellitus (DM). Challenges to managing type 2 diabetes (T2DM) in India are unique. Indian T2DM patients do not just present with DM alone, but with clustering of cardiovascular (CV) risk factors like hypertension (HTN), dyslipidemia, and obesity.

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Article Synopsis
  • * There are currently no unified guidelines for using steroids in diabetic patients, leading to inconsistencies among healthcare providers regarding the selection and application of different steroids.
  • * A consensus working group has emphasized the need for careful monitoring and individualized treatment plans to manage steroid-related complications effectively for diabetic patients.
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Recurrent aphthous stomatitis (RAS) is characterized by painful, oral mucosal ulcers with wide range of prevalence ranging from 2 to 78%. Etiology of RAS is idiopathic and multifactorial. There are numerous gaps in assessment and management of RAS and the absence of guidelines or a consensus document makes the treatment further difficult.

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Background: Hospital Episode Statistics (HES) data are used to measure surgical outcomes, but its quality has been considered inferior to that of clinical databases. We compare the recording accuracy of HES, an administrative database used in the National Health Service (NHS), with that of ACS NSQIP (American College of Surgeons National Surgical Quality Improvement Program), a well-established clinical database.

Methods: 1323 patient records from our hospital, common to both databases were compared for ten surgical procedures (amputation, appendicectomy, cholecystectomy, femoral hernia repair, Hartmann's procedure, incisional hernia repair, inguinal hernia repair, long saphenous vein surgery, parathyroidectomy and umbilical hernia repair) and nine postoperative complications (acute renal failure, myocardial infarction, pneumonia, pulmonary embolism, urinary tract infection, blood transfusion, septic shock, surgical site infection and wound disruption) using text strings or ICD-10 (International Classification of Diseases) codes.

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A 43-year-old woman presented with a few weeks' history of discomfort and swelling in her left breast. She had undergone bilateral breast augmentation 8 years previously. There were no risk factors for breast cancer.

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A 12-year-old girl presented with a sudden onset of per rectal bleeding. After admission, she had further episodes of large volume per rectal bleeding and developed hypotensive shock. Hence a massive haemorrhage protocol was activated.

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