Survival predictors of interstitial lung disease in India: Follow-up of Interstitial Lung Disease India registry.

Background: Predictors of survival for interstitial lung disease (ILD) in the Indian population have not been studied. The primary objective of the study was to assess the Modified-Gender Age and Physiology (M-GAP) score to predict survival in patients with ILD seen in clinical practice. We also analyzed the role of demographic and radiological characteristics in predicting the survival of patients with ILD.

Interstitial Lung Disease in India. Results of a Prospective Registry.

Rationale: Interstitial lung disease (ILD) is a heterogeneous group of acute and chronic inflammatory and fibrotic lung diseases. Existing ILD registries have had variable findings. Little is known about the clinical profile of ILDs in India.

Detection of lungs status using morphological complexities of respiratory sounds.

Traditionally, the clinical diagnosis of a respiratory disease is made from a careful clinical examination including chest auscultation. Objective analysis and automatic interpretation of the lung sound based on its physical characters are strongly warranted to assist clinical practice. In this paper, a new method is proposed to distinguish between the normal and the abnormal subjects using the morphological complexities of the lung sound signals.

An automated tool for localization of heart sound components S1, S2, S3 and S4 in pulmonary sounds using Hilbert transform and Heron's formula.

The primary problem with lung sound (LS) analysis is the interference of heart sound (HS) which tends to mask important LS features. The effect of heart sound is more at medium and high flow rate than that of low flow rate. Moreover, pathological HS obscures LS in a higher degree than normal HS.

In vitro regeneration through organogenesis and somatic embryogenesis in pigeon pea [ Cajanus cajan (L.) Millsp.] cv. JKR105.

In vitro regeneration of pigeon pea through organogenesis and somatic embryogenesis was demonstrated with pigeon pea cv. JKR105. Embryonic axes explants of pigeon pea showed greater regeneration of shoot buds on 2.

An alternative therapy for idiopathic pulmonary fibrosis by doxycycline through matrix metalloproteinase inhibition.

Background: Idiopatiic pulmonary fibrosis (IPF) is a disease of dysregulated fibrogenesis with abnormal matrix metalloproteinase (MMPs) activity, angiogenesis, and profibrotic milieu wherein MMPs inhibition appears to be target-based therapy. We evaluated the role of doxycycline as a nonspecific inhibitor of MMPs in IPF patients.

Materials And Methods: Patients of IPF diagnosed on the basis of ATS-ERS consensus criteria were put on oral doxycycline in an open prospective trial.