Int J Gynaecol Obstet
February 2025
In addressing the Sustainable Development Goals (SDGs) the UNDP has fixed 17 issues out of them clean water (SDG-6) and affordable energy (SDG-7) serve as decisive points towards sustenance of the society. Material chemistry plays a vital role to design new chemical compounds and exploring versatile activities towards the solution of pressing challenges. Copper, third abundant metal in human body following iron and zinc, is useful to monitor many metabolic processes.
View Article and Find Full Text PDFCorrection for 'Structure-directing effect of terephthalate in bridging Zn(II)- and Cd(II)-based coordination polymers towards application in the detection of trace quantities of Pd in aqueous media and their electrical conductivities' by Koushik Saha , , 2025, https://doi.org/10.1039/d4dt03075c.
View Article and Find Full Text PDFEnergy crisis and environmental pollution are two central themes of contemporary research towards achieving sustainable development goals (SDGs). Material chemistry is the chief discipline that can resolve glitches in these areas through the appropriate design of chemical compounds with multifunctional properties. In this regard, two stable coordination polymers (CPs) were synthesised in this work using Zn(II) (3d) and Cd(II) (d) metal nodes with 1,4-benzenedicarboxylate () as the bridging ligand and monodentate pyridyl-N coordinated 9-fluoren-2-yl-pyridin-4-ylmethylene-amine (flpy) as the fluorogenic partner.
View Article and Find Full Text PDFDiagnostic approaches that combine the high sensitivity and specificity of laboratory-based digital detection with the ease of use and affordability of point-of-care (POC) technologies could revolutionize disease diagnostics. This is especially true in infectious disease diagnostics, where rapid and accurate pathogen detection is critical to curbing the spread of disease. We have pioneered an innovative label-free digital detection platform that utilizes Interferometric Reflectance Imaging Sensor (IRIS) technology.
View Article and Find Full Text PDFJ Am Med Inform Assoc
January 2025
Clinical trials show that lumacaftor/ivacaftor (LUM/IVA) treatment has the potential to modify early cystic fibrosis (CF) disease progression in children as young as 2 years of age. To assess the long-term impact of LUM/IVA treatment on CF disease progression in children aged 2-5 years. This phase 2 trial had two parts: part 1, a 48-week, randomized, double-blind, placebo-controlled study of LUM/IVA in children aged 2-5 years (previously reported) was followed by a 48-week open-label treatment period in which all children received LUM/IVA (part 2; reported here).
View Article and Find Full Text PDFUnder the gravity of future socio-economic development, the viability of water electrolysis still hinges on the accessibility of stable earth-abundant electrocatalysts and net energy efficiency. This work emphasizes the design and synthesis of two newly developed cobalt(II) complexes, [Co(HL)(NCS)] (Comono) and [Co(L)(CHOH)]ClO (Codi), with a (N,O)-donor ligand, HL (2-methoxy-6-(((2-methoxyphenyl)imino)methyl)phenol). The study delves into understanding their structural, morphological, magnetic, and charge transport characteristics.
View Article and Find Full Text PDFDiagnostic approaches that combine the high sensitivity and specificity of laboratory-based digital detection with the ease of use and affordability of point-of-care (POC) technologies could revolutionize disease diagnostics. This is especially true in infectious disease diagnostics, where rapid and accurate pathogen detection is critical to curbing the spread of disease. We have pioneered an innovative label-free digital detection platform that utilizes Interferometric Reflectance Imaging Sensor (IRIS) technology.
View Article and Find Full Text PDFThe continuing mutability of the SARS-CoV-2 virus can result in failures of diagnostic assays. To address this, we describe a generalizable bioinformatics-to-biology pipeline developed for the calibration and quality assurance of inactivated SARS-CoV-2 variant panels provided to Radical Acceleration of Diagnostics programs (RADx)-radical program awardees. A heuristic genetic analysis based on variant-defining mutations demonstrated the lowest genetic variance in the Nucleocapsid protein (Np)-C-terminal domain (CTD) across all SARS-CoV-2 variants.
View Article and Find Full Text PDFIn this study, we report the synthetic method of two distinct supramolecular metallogels, namely Mn-BDA and Cd-BDA, using Mn(II) acetate tetrahydrate, Cd(II) acetate dihydrate and butane-1,4-dicarboxylic acid (BDA). DMF, a polar aprotic solvent, was immobilized in both metallogel-networks for their synthesis. The metallogelation of Mn-BDA was successfully attained through the instant mixing of a Mn(II)-source and BDA in DMF solvent media.
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