Feature Selection Through Message Passing.

A novel similarity-based feature selection algorithm is developed, using the concept of distance correlation. A feature subset is selected in terms of this similarity measure between pairs of features, without assuming any underlying distribution of the data. The pair-wise similarity is then employed, in a message passing framework, to select a set of exemplars features involving minimum redundancy and reduced parameter tuning.

Dielectric and Raman investigations of structural phase transitions in (C2H5NH3)2CdCl4.

Temperature-dependent Raman and dielectric measurements have been carried out on (C2H5NH3)2CdCl4 single crystals. Raman studies reveal the presence of two structural phase transitions below room temperature at 216 K and 114 K. The phase transitions are marked by anomalies in temperature dependence of wave-number and full width half maximum (FWHM) of several vibrational modes.

Allosteric transition induced by Mg²⁺ ion in a transactivator monitored by SERS.

We demonstrate the utility of the surface-enhanced Raman spectroscopy (SERS) to monitor conformational transitions in protein upon ligand binding. The changes in protein's secondary and tertiary structures were monitored using amide and aliphatic/aromatic side chain vibrations. Changes in these bands are suggestive of the stabilization of the secondary and tertiary structure of transcription activator protein C in the presence of Mg(2+) ion, whereas the spectral fingerprint remained unaltered in the case of a mutant protein, defective in Mg(2+) binding.