Ultrastructural and proteomic evidence for the presence of a putative nucleolus in an Archaeon.

Nucleoli are subcellular compartments where transcription and maturation of pre-ribosomal RNAs occur. While the transcription of ribosomal RNAs is common to all living cells, the presence and ultrastructure of nucleoli has been only documented in eukaryotes. Asgard-Archaea, the closest prokaryotic relatives of eukaryotes, and their near relatives TACK-Archaea have homologs of nucleolar proteins and RNAs in their genome, but the cellular organization of both is largely unexplored.

Evolutionary Cell Biology (ECB): Lessons, challenges, and opportunities for the integrative study of cell evolution.

Evolutionary Cell Biology (ECB) has gained increasing attention in the last decades. Here we explore whether ECB is truly inter-disciplinary through the combination of cellular and evolutionary biology to offer evidence-based insights regarding the major questions of cell evolution. Since 2012, ECB asserts to utilize the increasing potential of high-throughput omics data () with morpho-functional () information, although challenges remain for a complete integration.