Publications by authors named "Parrilla P"

Article Synopsis
  • Tityus caripitensis is an endemic scorpion from northeastern Venezuela, causing sting incidents, and this study is the first to explore its venom's biological, biochemical, and electrophysiological properties.
  • The venom exhibits toxicity to mice with an LD50 of 20.2 μg/gr, and SDS-PAGE analysis identified 7 protein fractions, including potential neurotoxins in the 6-8 kDa range.
  • The venom caused significant changes in blood chemistry and affected sodium and potassium ion channels, and while it is less toxic than Tityus discrepans, they share molecular similarities that are important for antivenom treatment.
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Article Synopsis
  • - The COVID-19 pandemic has significantly impacted liver transplant patients, particularly those who are immunosuppressed, leading to higher severity and mortality rates from SARS-CoV-2 infections.
  • - A report analyzed three liver transplant patients (two women, one man) who all needed intensive care; two died while one recovered after treatment with tocilizumab.
  • - The study highlights a COVID-19 outbreak within a liver transplant ward, aiming to improve understanding and treatment strategies for similar cases in the future.
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Background: the management of postoperative esophageal leaks is a huge therapeutic challenge. Thanks to the advances in endoscopy, treatment with esophageal stents has been proposed as a valid option.

Aims: the main objective of the study was to evaluate the effectiveness and safety of the use of fully covered esophageal metal stents in the treatment of postoperative esophageal leaks.

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Introduction: rectoscopy and 18F-FDG PET/CT as a diagnostic algorithm for the assessment of tumor response in rectal cancer after neoadjuvant chemoradiation therapy (CRT) is very useful.

Material And Methods: this was a prospective longitudinal study in patients with locally advanced rectal cancer treated with neoadjuvant CRT. Patients were assessed after CRT completion with a digital rectal examination, proctoscopy and 18F-FDG PET/CT.

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Background: Cuba is one of the Latin American countries with the highest rates of organ donation. Social and cultural differences among the population throughout the country may also affect attitudes toward donation. Knowledge of these characteristics would facilitate awareness of the population most reluctant to donate and transplant.

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Introduction: Resilience is the ability to recover or adequately face adverse situations. It acts as a protective factor against negative events and/or complex stages of life, such as a chronic and complex disease requiring liver transplant. Age can also have an effect on a patient's ability to deal with liver transplant, resilience here being a predictor of well-being.

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Unlabelled: The knowledge acquired during university education about organ donation and transplantation (ODT) decisively influences the information future health professionals transmit. This is important in ODT where the participation of the general public is essential to obtain organs.

Objective: To determine notions of Spanish medicine and nursing students on ODT and its relationship with attitude toward ODT.

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Introduction: There are differences in the attitude toward organ donation between Latin Americans living in Spain and those living in the United States.

Objective: We sought to analyze the socio-personal factors that can condition the difference in attitude toward donation between Latin Americans living in the United States and those living in Spain.

Materials And Methods: Participants in the study were Latin Americans living in Spain (group A; n=1237) and the United States (Florida) (group B; n=1450), extracted from the database of the International Collaborative Donor Project (PCID).

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Introduction: The African population is one of the largest immigrant groups in Europe. Religious beliefs are deeply rooted in most African societies and condition their attitude toward organ donation.

Objective: We sought to analyze the influence of Catholicism in the attitude toward organ donation among Africans residing in Spain.

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Unlabelled: A primary care physician (PCP) not only accompanies the patient in the process of an illness, but throughout his or her life. The confidence we have in these health professionals is fundamental, and their favorable attitude toward organ donation and transplantation (ODT) has a significant influence on the population.

Objective: To analyze trust in PCPs among Spanish medical and nursing students, the relationship with their attitude toward ODT, and the factors that condition it.

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Introduction: Despite sensitization of medical students toward the donation of organs, a non-negligible percentage of students are not in favor of donation.

Objective: To analyze the reasons of Spanish medical students who do not have a favorable attitude toward the donation of their own organs after death.

Method: The population under study is medical students in Spanish universities, using the database of the International Donor Collaborative Project, stratified by geographic area and academic year.

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Introduction: Living kidney donation (LKD) is one of the most used alternatives in the field of organ transplantation.

Objective: Analyze the attitude toward LKD among the population of Havana, Cuba.

Methods: Population under study.

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Introduction: Awareness of organ donation among Spanish doctors and medical students is very positive. However, the emerging group of professionals of non-Spanish nationality studying in Spain has not been analyzed.

Objective: To analyze the differences in the attitudes toward the different types of donation among medical students, according to their nationality.

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Introduction: Health professionals are asked to promote health, especially organ transplantation; however, they do not always have specific training.

Objective: To analyze information about donation and organ transplantation among Spanish medical students.

Method: The population under study is medical students in Spanish universities using the database of the International Donor Collaborative Project, stratified by geographic area and academic year (n = 9275).

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Background: Living donation is a potential source of organs that could help to reduce the organ transplant deficit. Given that we have a worldwide aging population, it is important to assess the opinion of older people toward this type of donation.

Objectives: To analyze the attitude of people aged > 65 years toward living kidney donation (LKD) and living liver donation (LLD) and to investigate the variables affecting their attitudes.

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Introduction: Algeria is an important source of immigrants to Europe. A population with a low culture of donation and transplantation and little knowledge of related concepts such as brain death (BD).

Objective: Analyze the knowledge and acceptance of the BD concept of the population born in Algeria and residing in Spain.

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Background: Worldwide population aging has resulted in changes in the approach to the organ donation and transplantation (ODT) process, forcing us to include older people on transplant waiting lists and to assess older patients as potential donors. However, this is a sector of the population that has not been studied in great detail in terms of the information they receive about ODT.

Objectives: To analyze what kinds of media provide people > 65 years of age with information about ODT and which sources of information affect their attitude about this subject.

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Introduction: Spain is a great receptor of immigration from sub-Saharan people like the Senegalese. This population is not very familiar with the process of organ donation and transplantation, and even less toward new therapies related to transplantation, such as xenotransplantation (XenoTx).

Objective: Analyze the attitude toward XenoTx among the Senegalese population living in Spain.

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Background: The concept of brain death (BD) is not well understood in the general population; this lack of knowledge is one of the main factors that generates an attitude against organ donation. Older people are a population group that has rarely been studied in relation to organ donation and transplantation (ODT), and it is important to investigate the most important aspects of ODT, such as people's concept of BD.

Objectives: To analyze the level of understanding of the concept of BD in people > 65 years of age and the factors that influence their mode of thinking.

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Introduction: The attitude toward living liver donation (LLD) among the Spanish population is mostly positive; however, the reality is that liver transplants from live donations are currently minimal. Given this situation, studies that analyze these discrepancies should be carried out.

Objective: Analyze the attitude toward LLD among family members of patients on the waiting list for liver transplantation.

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Article Synopsis
  • - The study investigates the attitudes of Ghanaians living in Spain towards related living kidney donation (LKD), revealing that 72% support LKD, while 28% are against it or unsure.
  • - Factors influencing attitudes toward LKD include knowledge of organ donation, social interactions, religious beliefs, and concerns about health risks associated with donation.
  • - Compared to other Western populations, Ghanaians in Spain display a more negative attitude towards related LKD, largely due to psychosocial factors affecting their perceptions.
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Introduction: New transplant-related therapies such as xenotransplantation of solid cells, tissues, and organs are still poorly understood, especially in countries without preclinical xenotransplantation programs.

Objective: Analyze the attitude toward xenotransplantation among the population of Santiago de Cuba.

Method: Type of study.

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Introduction: In liver transplantation, living donation shows better and better results. However, rates of living liver donation (LLD) are low.

Objective: To analyze the attitude towards LLD among patients on the waiting list for liver transplantation.

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Introduction: A favorable attitude toward organ donation and transplantation (ODT) is fundamental among health professionals at the time of transplant promotion. In this sense, the training and awareness of professionals are fundamental.

Objective: To analyze the differences in the attitude toward ODT and the factors that condition it among Andalusian medical and nursing students.

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Introduction: Ecuadorians are the largest immigrant group in Spain. In countries with preclinical programs of xenotransplantation (XenoTx), it is important to know the population attitude toward them; however, in the Ecuadorian population it is not known.

Objective: To analyze the attitude toward XenoTx of organs among the Ecuadorian population residing in Spain.

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