Publications by authors named "Paromitta Datta"
Correction: Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer.
Devalingam Mahalingam Salih Hanni Anthony V Serritella Christos Fountzilas Joel Michalek Paromitta Datta
Oncotarget
October 2023
Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer.
Devalingam Mahalingam Salih Hanni Anthony V Serritella Christos Fountzilas Joel Michalek Paromitta Datta
Oncotarget
June 2023
Background: Androgen deprivation therapy (ADT) can lead to metabolic syndrome (MS) and is implicated in ADT-resistance. Metformin showed antineoplastic activity through mTOR inhibition secondary AMPK-activation.
Materials And Methods: To investigate whether metformin mitigated ADT-related MS, we conducted a randomized double-blind phase II trial of metformin 500 mg TID or placebo in non-diabetic patients with biochemically-relapsed or advanced PC due for ADT.