Publications by authors named "Parker Li"
Article Synopsis
- * A study found that higher expression of Plant homeodomain finger protein 6 (PHF6) in UCEC tissues correlates with poorer patient survival, while mutations in PHF6 can lead to better outcomes.
- * Reducing PHF6 levels in cancer cells inhibited their growth and enhanced immune response, suggesting that PHF6 could serve as a valuable biomarker and potential therapeutic target for treating UCEC.
Article Synopsis
- This study aims to identify a new genetic signature in rectal cancer to improve survival predictions and inform immunotherapy choices.
- Researchers analyzed gene expression data from rectal cancer patients and discovered 468 differentially expressed genes (DEGs), ultimately narrowing it down to a 5-gene signature (CLIC5, ENTPD8, PACSIN3, HGD, and GNG7) to calculate risk scores.
- The findings suggest that higher risk scores correlate with poorer overall survival and show significant interactions with immune cells, indicating potential pathways for enhancing treatment strategies in rectal cancer patients.
Background: Glioblastoma (GBM) is one of the most common and aggressive primary malignant brain tumors with severe symptoms and a poor prognosis. Leptomeningeal dissemination (LMD) is a serious complication of GBM that often results in dire outcomes. There is currently no effective treatment.
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- * ELF-PEMF is a low-frequency magnetic field with minimal side effects, but its use in glioma treatment is uncommon.
- * The review discusses five key mechanisms of ELF-PEMF in glioma therapy and explores its potential alongside traditional treatments, offering insights for oncologists.*
Background: Diagnosing primary central nervous system lymphoma (PCNSL) remains a challenge. MicroRNAs (miRNAs) are promising noninvasive markers for the identification of PCNSL. The present study aims to assess the diagnostic value of miRNAs for PCNSL patients as biomarkers.
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