Publications by authors named "Parisha Shrestha"
The World Health Organization (WHO) in 2008 recommended the use of currently licensed typhoid vaccines using a high risk or targeted approach. The epidemiology of disease and the vaccine characteristics make school-based vaccination most feasible in reducing typhoid disease burden in many settings. To assess feasibility of school-based typhoid vaccination, two districts in Kathmandu, Nepal and two towns in Karachi, Pakistan were selected for pilot program.
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- Salmonella Typhi has been linked to serious infections and high mortality, leading to the replacement of older vaccines with the new Vi polysaccharide (ViPS) vaccine.
- Despite the availability of the ViPS vaccine for over 25 years, Nepal continues to experience a high incidence of typhoid fever, with 1,881 confirmed cases reported between January 2008 and July 2012, primarily among children.
- It is essential to prioritize vaccination alongside improvements in water and sanitation to effectively control typhoid in Nepal and other endemic regions in Asia and Africa.