Publications by authors named "Parish A"

Negative attitudes toward persons with disabilities (PWDs) can lead to stigmatization and exclusion, underscoring the need for effective tools to measure and address such attitudes in educational settings. This study compares the psychometric properties of two scales used to assess attitudes toward PWDs among health science learners: the Multidimensional Attitudes Scale Toward Persons with Disabilities (MAS) and the Attitudes and Perspectives Toward Persons with Disabilities Scale (APPD). This research examines the internal consistency, factor stability, factor replicability, and convergent validity of these scales across different measurement occasions using data from second-year Medical (n = 102) and Doctor of Physical Therapy (n = 39) students.

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Importance: Few person-centered, scalable models of collaborative intensive care unit (ICU) clinician-palliative care specialist care exist.

Objective: To evaluate the effect of a collaborative palliative care intervention compared to usual care among family members of patients in the ICU.

Design, Setting, And Participants: This parallel-group randomized clinical trial with patient-level randomization was conducted between April 2021 and September 2023.

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As the population ages, the prevalence of cognitive impairment due to neurodegenerative diseases such as Alzheimer disease (AD) is expected to double in the United States to nearly 14 million over the next 40 years. AD and related dementias (ADRD) are a leading cause of morbidity and mortality and among the costliest to society. Although emerging biomedical interventions for ADRD focus on early stages and are currently limited to AD, care management can benefit patients with ADRD across the disease course.

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Disability is extremely common, and there is a need for high quality medical school curricula on working with persons with disabilities. The goal of disability training is to provide the proper knowledge and skills to address the unique needs of PWD, mitigate health disparities, and help shape more compassionate and informed physicians. This article presents 12 tips to incorporate disability training into undergraduate medical education.

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Many medical schools in the United States (US) have employed policies and programming to prevent mistreatment and encourage students to report mistreatment events. Yet, there is little evidence showing a large-scale decrease in mistreatment behaviors overall, and, in many cases, mistreatment events go unreported. This study examines views from medical students and faculty for preventing mistreatment during medical training, as well as strategies for encouraging learners to report mistreatment events when they occur.

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Objective: To evaluate postoperative outcomes among patients undergoing colon surgery who receive perioperative prophylaxis with ertapenem compared to other antibiotic regimens.

Design And Setting: Multicenter retrospective cohort study among adults undergoing colon surgery in seven hospitals across three health systems from 1/1/2010 to 9/1/2015.

Methods: Generalized linear mixed logistic regression models were applied to assess differential odds of select outcomes among patients who received perioperative prophylaxis with ertapenem compared to other regimens.

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Introduction: Patients with type 2 diabetes (T2D), particularly those from historically marginalized racial and ethnic groups, are at high risk of poor outcomes from metabolic dysfunction-associated steatotic liver disease (MASLD). Evidence-based management (EBM) of MASLD can prevent its progression to cirrhosis and poor outcomes, yet rates of EBM of MASLD are low in T2D.

Methods: In this pilot study of ten participants, we examined the feasibility and acceptability of a telehealth intervention that delivered EBM of MASLD in Latino/a and Black patients with T2D in the Duke Healthcare System.

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Objective: We assessed the real-world performance of stool-based tests (SBTs) for colorectal cancer screening.

Materials And Methods: Retrospective review of average-risk individuals with positive SBT for advanced neoplasia (adenocarcinoma, advanced adenoma, and/or advanced serrated lesions) detection at follow-up colonoscopy.

Results: There was no statistical difference in the detection of advanced neoplasia (P= 0.

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Unlabelled: Persons with disabilities (PWD) often require special accommodations and more comprehensive healthcare yet frequently have encounters with physicians who are unprepared to provide tailored and complete care. A multipronged disability awareness curriculum for second-year medical students was implemented, including content on disability etiquette, patient-centered and interprofessional learning sessions for individuals with physical disabilities and intellectual and developmental disabilities, and a debriefing session with physiatrists. The objective of this study was to utilize a mixed methods approach to evaluate the disability awareness curriculum in undergraduate medical education (UME).

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Article Synopsis
  • Data on chronic hypoxemia risk factors in low- and middle-income countries are limited; this study aimed to identify such factors among hospitalized adults in Kenya.
  • The study involved a case-control design with 108 patients having chronic hypoxemia and 240 non-hypoxemic control patients, revealing significant associations with older age, female sex, tobacco use, and prior tuberculosis.
  • The results suggest a strong link between past tuberculosis and chronic lung disease in Kenya, emphasizing the need for further research on this issue.
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Objective: To assess frequency of evidence-based management (EBM) of metabolic dysfunction-associated steatotic liver disease (MASLD) in patients with type 2 diabetes (T2D), and to examine for racial/ethnic disparities in the receipt of EBM.

Methods: We conducted a cross-sectional analysis of patients with T2D and presumptive MASLD in an academic health care system between 2019 and 2021. Presumptive MASLD was defined as at least 1 alanine aminotransferase value ≥30 U/L with exclusions for alcohol overuse, viral hepatitis, liver transplantation, chemotherapy use, and liver disease other than MASLD.

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This report highlights the 2023-2028 American Association of Nurse Practitioners Research Agenda (AANP-RA), which focuses on the research goals of AANP as an organization and is based on its mission and strategic plan. The purpose of the AANP Research Agenda is to outline research priorities that advance the AANP Strategic Plan and concurrently address gaps in nursing science. American Association of Nurse Practitioners supports research studies that are rigorously designed and conducted using quantitative, qualitative, and mixed-methods approaches, as well as implementation science with the potential to positively impact both NP practice and patient health outcomes.

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  • A study shows that nasal swabs for MRSA in adults are effective in ruling out MRSA pneumonia.
  • There is limited data on this topic for children, which this study addresses.
  • The research analyzed 505 pediatric patients and found a 99.8% negative predictive value for those suspected of having respiratory infections.
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Objective: Real-world data is crucial to inform existing opportunistic colorectal cancer (CRC) prevention programs. This study aimed to assess CRC screening adherence and utilization of various screening modalities within a Primary Care network over a three-year period (2017-2019).

Methods: A retrospective review of individuals aged 50-75 years at average CRC risk, with at least one clinic visit in the previous 24 months.

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We describe a 15-year-old boy who presented with low back pain due to vertebral compression fractures, growth deceleration, excessive weight gain, rounded facies, dorsocervical fat pad, and hypertension. He was diagnosed as having Cushing syndrome (CS) due to primary pigmented nodular adrenocortical disease resulting in excess cortisol produced by the adrenal glands, leading to disruption of the hypothalamic-pituitary-adrenal axis. The most common cause of CS is exogenous glucocorticoids, with endogenous causes being extremely rare, often leading to delay in diagnosis or misdiagnosis.

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The plant cytokinetic microtubule array, called the phragmoplast, exhibits higher microtubule dynamics in its center (midzone) than at the periphery (distal zone). This behavior is known as the axial asymmetry. Despite being a major characteristic of the phragmoplast, little is known about regulators of this phenomenon.

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Introduction: Metabolic dysfunction-associated steatohepatitis (MASH) is highly prevalent in type 2 diabetes (T2D). Pioglitazone and glucagon-like peptide-1 receptor agonists (GLP-1RA) are medications used in T2D that can resolve MASH and should be considered in all patients with T2D and MASH. We assessed prescription rates of evidence-based T2D pharmacotherapy (EBP) in MASH, and ascertained racial/ethnic disparities in prescribing.

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Article Synopsis
  • Alcohol is a significant cause of preventable deaths in the U.S., and this study aimed to evaluate the occurrence of phenobarbital-resistant alcohol withdrawal syndrome (AWS) and its risk factors.
  • The study compared two groups of patients who received either a standard or low dose of phenobarbital (PHB) while being treated for AWS, but found no significant difference in the rate of PHB-resistant cases between the two groups.
  • The only notable risk factor found for developing PHB-resistant AWS was the total dose of benzodiazepines taken in the 24 hours prior to receiving PHB.
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  • The study aimed to assess the burden of hypoxaemia among hospitalized adults in Kenya, focusing on its prevalence and chronic forms in low-to-middle income settings.
  • Conducted at a national referral hospital from September 2019 to April 2022, the research involved adults admitted to general medicine wards, with nearly a quarter of admitted patients found to be hypoxaemic upon arrival.
  • Results indicated that 23.8% of the 4,104 screened patients were hypoxaemic at admission, with a mortality rate of 31.0% among those with unresolved hypoxaemia, and a chronic hypoxaemia prevalence of 2.1% in the total population, highlighting significant patient outcomes related to oxygen access and treatment
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Background: Sensitized lung transplant recipients are at increased risk of developing donor-specific antibodies, which have been associated with acute and chronic rejection. Perioperative intravenous immune globulin has been used in sensitized individuals to down-regulate antibody production.

Methods: We compared patients with a pre-transplant calculated panel reactive antibody ≥25% who did not receive preemptive immune globulin therapy to a historical control that received preemptive immune globulin therapy.

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Article Synopsis
  • - The COVID-19 pandemic increased psychological distress and burnout among frontline healthcare workers, particularly nurses, leading to a need for effective intervention methods.
  • - A pilot randomized trial involving 102 nurses tested the feasibility and impact of a mobile mindfulness program aimed at reducing psychological distress and burnout, comparing intervention participants with a control group on various mental health metrics over a month.
  • - Results showed that while the mindfulness intervention effectively reduced depression symptoms (as measured by the Patient Health Questionnaire-9), it did not significantly impact burnout levels, indicating limited use of the program among participants despite meeting initial feasibility targets.
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The incidence and risk factors for propofol-associated hypertriglyceridemia (HTG) in patients receiving extracorporeal membrane oxygenation (ECMO) have not been evaluated. The purpose of this study was to determine the incidence and risk factors for propofol-associated HTG in patients with acute respiratory distress syndrome (ARDS) on ECMO. This retrospective, cohort study included 167 adults admitted to a medical intensive care unit (ICU) from July 1, 2013 to September 1, 2021, who received 24 hours of concurrent propofol and ECMO therapy.

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Despite the increased risk of non-adherence, allograft rejection, and mortality following transfer from pediatric to adult care in liver transplantation (LT), there is no standardized approach to health care transition (HCT). Two electronic national surveys were developed and distributed to members of the Society for Pediatric Liver Transplantation and all adult LT programs in the United States to examine current HCT practices. Responses were received from 40 pediatric and 79 adult centers.

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Dementia with Lewy bodies is the second most common type of neurodegenerative dementia in older adults. NPs in primary care must have a thorough understanding of this complex disease in order to ensure appropriate referrals, provide patient and caregiver education, and comanage this disease with other healthcare professionals.

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The prevalence of mental health disorders is rising with the coronavirus of 2019 pandemic, and millions of Americans reside in areas with mental health professional shortages. Primary care providers have an opportunity to provide care for commonly occurring mental health disorders. Using a holistic conceptualization of recovery in mental illness, this report provides evidence-based guidance for initiation, titration, and discontinuation of pharmacotherapy for mild to moderate depression and anxiety in the primary care setting.

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