Synopsis of recent research by authors named "Parisa Zargar"
- Parisa Zargar's recent research focuses on enhancing the effectiveness of chemotherapy agents, particularly cisplatin and 5-fluorouracil, in treating resistant cancer types such as bladder and colorectal cancer.
- In her 2022 study, Zargar demonstrated that the downregulation of topoisomerases 1 and 2 with acriflavine can sensitize bladder cancer cells to cisplatin, potentially overcoming resistance to this common chemotherapy drug.
- Additionally, her 2018 research revealed that acriflavine increases the antitumor activity of 5-fluorouracil in colorectal cancer cells, suggesting a promising combination therapy to improve patient outcomes.
