Publications by authors named "Parisa Selseleh"

Mitochondria are widely recognized as sources of reactive oxygen species in animal cells, with HO being of particular note because it can act not only in oxidative stress but also is important to several signalling pathways. Lesser recognized is that mitochondria can have far greater capacity to consume HO than to produce it; however, the consumption of HO may be kinetically constrained by HO availability especially at the low nanomolar (or lower) concentrations that occur in vivo. The production of HO is a function of many factors, not the least of which are respiratory substrate availability and the protonmotive force (Δp).

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