Publications by authors named "Parisa Lakhshei"
Article Synopsis
- Apoptin is a promising anticancer protein that selectively induces apoptosis in tumor cells, particularly in breast cancer lines, highlighting its potential for cancer therapy.
- Researchers successfully created two forms of apoptin fusion proteins (SUMO-PTD4-Apoptin and PTD4-Apoptin) and tested their effects on breast cancer cells (MDA-MB-231 and MCF-7) and normal cells (MCF-10A) using various assays.
- Results showed that SUMO-PTD4-Apoptin demonstrated a lower IC50 value in cancer cells than in normal cells, indicating higher cytotoxicity, while PTD4-Apoptin had similar effects across both cancer
