Publications by authors named "Parisa Esmaeili Motlagh"
Purpose: Non-functioning pituitary adenomas (NFPAs) are a group of these neoplasms originated from the adenohypophyse and do not show evidence of hormonal oversecretion. However, different genes and lncRNAs have been found to be dysregulated in these samples.
Material And Methods: In this study, in order to identify novel biomarkers, a set of regulatory lncRNAs for the two important hub genes, i.
RORα is a transcription factor encoded by RORA gene. This protein is involved in several metabolic conditions, including obesity. We assessed association between two polymorphisms within this gene (namely rs11639084 and rs4774388) and severe obesity in Iranian population.
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- - Pituitary adenomas (PAs) are a significant type of brain tumor found in adolescents and young adults, yet the reasons behind their formation are still unclear, prompting ongoing research.
- - A recent study used bioinformatics to analyze pituitary adenoma tissue samples and identified changes in the expression of specific genes, particularly noting increased levels of HIF1A and MAPK1 and a decrease in BANCR in tumor tissues.
- - Although the research highlighted some notable gene expression changes, it also indicated that more investigations are necessary to fully understand the molecular mechanisms involved in the development of PAs.
Dental pulp cells, a unique source of ectomesenchymal pluripotent stem cells, are originated from the skull neural crest. They are considered as one ideal source of cells for the regenerative medicine applications. Cerebrospinal fluid (CSF), a transparent fluid found in the brain and spinal cord, is enriched with electrolytes, proteins, and growth factors such as EGF, bFGF, BDNF, GDNF, and neuropeptides and can be utilized as a trigger in order to induce the neural differentiation.
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