Decreased Susceptibility of Isolates to Azithromycin in Children in Tehran, Iran.

Azithromycin (AZT) has widely been used for the treatment of shigellosis in children. Recent studies showed a high rate of decreased susceptibility to azithromycin due to different mechanisms of resistance in isolates. Accordingly, the purpose of this study was to investigate the role of azithromycin resistance mechanisms of isolates in Iran during a two-year period.