Publications by authors named "Paris Singleton"

Adolescents strive for peer approval, and an increased sensitivity to peers' opinions is normative. However, among vulnerable adolescents, peer evaluation can be detrimental, contributing to affective disorders. It is, therefore, critical to improve our understanding of neural underpinnings of peer evaluation.

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Borderline personality disorder (BPD) is a complex and debilitating psychiatric illness. Prior research in adults has shown that neurophysiological deficits in feedback processing and learning from rewards may be central to the development of BPD; however, little research has examined these markers in adolescents and young adults with BPD. The present study used event-related potentials and time-frequency decomposition analysis to probe neural responses to wins and losses in a guessing task among 68 females (13 to 23 years old) either with BPD ( = 35) or no history of mental disorders (healthy control [HC]; = 33).

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Article Synopsis
  • The study investigates how cognitive-behavioral therapy (CBT) skills contribute to symptom improvement in clinically depressed adolescents, focusing on the distinction between cognitive and behavioral skills.
  • Data collected from a 12-week trial involved 33 adolescent females, analyzing both therapist and patient reports on CBT skills at multiple time points, alongside assessments of depressive symptoms.
  • Results show that variations in behavioral skills, particularly from session to session (within-patient effects), significantly predicted improvements in depressive symptoms, highlighting the need for more research on the specific roles of these skills in therapy outcomes.
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Altered reward processing is a transdiagnostic factor implicated in a wide range of psychiatric disorders. While prior animal and adult research has shown that stress contributes to reward dysfunction, less is known about how stress impacts reward processing in youth. Towards addressing this gap, the present study probed neural activation associated with reward processing following an acute stressor.

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Fear-potentiated startle (FPS) paradigms provide insight into fear learning mechanisms that contribute to impairment among individuals with posttraumatic stress symptoms (PTSS). Electrophysiology also has provided insight into these mechanisms through the examination of event-related potentials (ERPs) such as the P100 and LPP. It remains unclear, however, whether the P100 and LPP may be related to fear learning processes within the FPS paradigm.

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