Formation of sparsely tethered bilayer lipid membrane on a biodegradable self-assembled monolayer of poly(lactic acid).

The utilization of biomimetic membranes supported by advanced self-assembled monolayers is gaining attraction as a promising sensing tool. Biomimetic membranes offer exceptional biocompatibility and adsorption capacity upon degradation, transcending their role as mere research instruments to open new avenues in biosensing. This study focused on anchoring a sparsely tethered bilayer lipid membrane onto a self-assembled monolayer composed of a biodegradable polymer, functionalized with poly(ethylene glycol)-cholesterol moieties, for lipid membrane integration.

Providing multicolor plasmonic patterns with graphene quantum dots functionalized d-penicillamine for visual recognition of V(V), Cu (II), and Fe(III): Colorimetric fingerprints of GQDs-DPA for discriminating ions in human urine samples.

In this study, a novel fluorescent probe (graphene quantum dots functionalized d-penicillamine [GQDs-DPA]) was developed for the selective identification of Cu , V , and Fe among 26 types of metal ions, which considerably quench the fluorescence intensity of GQD. So, GQDs-DPA was applied as a simple fluorescent probe for facile metal ions recognition in standard solution. The proposed DPA-GQD supported amino acids respond to Cu , V , and Fe , with high sensitivity.

Visual monitoring and optical recognition of digoxin by functionalized AuNPs and triangular AgNPs as efficient optical nano-probes.

In this study, we presented elective, sensitive, and rapid UV-Vis spectrophotometry and calorimetric assay for the recognition of digoxin. Therefore, cysteamine-gold nanoparticles (Cys A-AuNPs) in the presence of cysteine acid amine and Silver nanoparticles in the presence of tetramethyl benzidine and hydrogen peroxide (AgNPs-TMB [3,3',5,5'-tetramethylbenzidine]-H O ) were synthesized and utilized as the desired probe. Finally, color variation of probes was observed in the absence and presence of digoxin.

Sensitive recognition of ractopamine using GQDs-DPA as organic fluorescent probe.

A novel spectrofluorimetric sensing platform was designed for Ractopamine measurement in aqueous and plasma samples. d-penicillamine functionalized graphene quantum dots (DPA-GQDs) was utilized as a fluorescence probe, which was synthesized through the pyrolysis of citric acid in the presence of DPA. This one-pot down-top strategy causes to high-yield controllable synthesis method.

An innovative genosensor for the monitoring of sequence using binding of pDNA to cDNA based on Cit-AgNPs.

considered as the most crucial epidemic-prone diseases according to the World Health Organization. Early diagnoses and therapy of infection is a great challenge since, it has no symptom and is resistance to drugs. Therefore, there is an urgent need for sensitive and precise detection of this pathogen.

DNA based biosensing of using nanoparticles aggregation method.

is the main cause of nosocomial infections in blood, urinary tract, wounds and in lungs leading to pneumonia. Apart from its strong predilection to be the cause of serious illnesses in intensive care units. Herein, we present a specific and sensitive approach for the monitoring of genome based on citrate capped silver nanoparticles (Cit-AgNPs) using spectroscopic methods.

A novel optical probe based on d-penicillamine-functionalized graphene quantum dots: Preparation and application as signal amplification element to minoring of ions in human biofluid.

In this study, d-penicillamine-functionalized graphene quantum dots (DPA-GQD) has been synthesized, which significantly increases the fluorescence intensity of GQD. We used this simple fluorescent probe for metal ions detection in human plasma samples. Designed DPA-GQD respond to Hg , Cu , Au , Ag , Co , Zn , and Pb with high sensitivity.

Spectrophotometric study of ketoconazole binding with citrate capped silver nanoparticles and its monitoring in human plasma samples.

Ketoconazole or Nizoral is an antifungal medication used to treat various type of fungal infections. It has been reported that this antifungal agent is able to induce a variety of heart function side effects, such as long-QT syndrome, and ventricular arrhythmias. Hence, prescribing, identifying and controlling the side effects of medications such as ketoconazole is essential for human safety.

Digoxin as a glycosylated steroid-like therapeutic drug: Recent advances in the clinical pharmacology and bioassays of pharmaceutical compounds.

Digoxin is cardiac glycosylated steroid like drug which is the fifth most commonly prescribed in US. Since the health of human population is largely determined by pharmacy they utilized, toxicity and side effects of pharmaceutics can put the safety of people in jeopardy and lead to some devastating impacts. Therefore, it is essential to detect and monitor small molecules like digoxin more meticulously.

Revolution in biomedicine using emerging of picomaterials: A breakthrough on the future of medical diagnosis and therapy.

Biomedicine is inseparable part of medicine that play vital role in modern medical progress. Bioimaging, smart drug delivery, safe cancer therapy and personalized medicine are some important properties of this science. Pico technology as a next frontier in a scientific filed will revolutionized the scientist world ubiquitously.

Dengue virus: a review on advances in detection and trends - from conventional methods to novel biosensors.

Dengue virus is an important arbovirus infection which transmitted by the Aedes female mosquitoes. The attempt to control and early detection of this infection is a global public health issue at present. Because of the clinical importance of its detection, the main focus of this review is on all of the methods that can offer the new diagnosis strategies.

Carbon based nanomaterials for tissue engineering of bone: Building new bone on small black scaffolds: A review.

Tissue engineering is a rapidly-growing approach to replace and repair damaged and defective tissues in the human body. Every year, a large number of people require bone replacements for skeletal defects caused by accident or disease that cannot heal on their own. In the last decades, tissue engineering of bone has attracted much attention from biomedical scientists in academic and commercial laboratories.

Biomedical applications of nanoflares: Targeted intracellular fluorescence probes.

Nanoflares are intracellular probes consisting of oligonucleotides immobilized on various nanoparticles that can recognize intracellular nucleic acids or other analytes, thus releasing a fluorescent reporter dye. Single-stranded DNA (ssDNA) complementary to mRNA for a target gene is constructed containing a 3'-thiol for binding to gold nanoparticles. The ssDNA "recognition sequence" is prehybridized to a shorter DNA complement containing a fluorescent dye that is quenched.