Preparation and characterization of mangiferin-loaded polylactic acid nanofiber mat with antioxidant and anti-browning properties for the development of food packaging products.

In this study, antioxidant nanofiber-based food packaging material composed of polylactic acid (PLA) and mangiferin (MG) was produced to reduce food spoilage. To this end, MG was extracted from Mangifera indica and chemically characterized. In vitro assays for scavenging several radical ions showed excellent antioxidant properties of MG.

One-Pot Extraction of Bioresources from Human Hair via a Zero-Waste Green Route.

In recent years, the extraction of bioresources from biowaste via green chemistry and their utilization for the production of materials has gained global momentum due to growing awareness of the concepts of sustainability. Herein, we report a benign process using an ionic liquid (IL), 1-butyl-3-methylimidazolium chloride ([BMIM]Cl), for the simultaneous extraction of keratin and melanin from human hair. Chemical characterization, secondary structure studies, and thermal analysis of the regenerated protein were performed thoroughly.

Strategies toward development of antimicrobial biomaterials for dental healthcare applications.

Several approaches for elimination of oral pathogens are being explored at the present time since oral diseases remain prevalent affecting approximately 3.5 billion people worldwide. Need for antimicrobial biomaterials in dental healthcare include but is not restricted to designing resin composites and adhesives for prevention of dental caries.

Development of a cancer-marker activated enzymatic switch from the herpes simplex virus thymidine kinase.

Discovery of new cancer biomarkers and advances in targeted gene delivery mechanisms have made gene-directed enzyme prodrug therapy (GDEPT) an attractive method for treating cancer. Recent focus has been placed on increasing target specificity of gene delivery systems and reducing toxicity in non-cancer cells in order to make GDEPT viable. To help address this challenge, we have developed an enzymatic switch that confers higher prodrug toxicity in the presence of a cancer marker.

A Positive Selection for Nucleoside Kinases in E. coli.

Engineering heterologous nucleoside kinases inside E. coli is a difficult process due to the integral role nucleosides play in cell division and transcription. Nucleoside analogs are used in many kinase screens that depend on cellular metabolization of the analogs.

Complex formation equilibria between 1-hydroxy-7-sulpho-2-naphthoic or 1-hydroxy-4,7-disulpho-2-naphthoic acid and iron(III) in 0.1M NaClO4 medium.

The equilibria for formation of iron(III) complexes with 1-hydroxy-7-sulpho-2-naphthoic and 1-hydroxy-4,7-disulpho-2-naphthoic acids in aqueous 0.1M sodium perchlorate medium at 25 degrees have been studied by spectrophotometric and potentiometric methods. The data are well described in terms of a series of stepwise complexes, FeL((3-rn)+)(r) in both systems (L(n-) denotes the unprotonated ligand anion).

The protonation and dimerization of 2,4-, 2,5-, 2,6-and 3,5-dihydroxybenzoic acids in 0.5M sodium perchlorate medium.

The protonation equilibria of 2,4-, 2,5-, 2,6- and 3,5-dihydroxybenzoic acids were studied by means of potentiometric titrations at I = 0.5 (NaClO(4)) and 25 degrees . The dimeric species H(6)L(2) and H(5)L(2) were found to form as well as the monomeric species H(p)L in the acidic solutions of 2,4- and 3,5-dihydroxybenzoic acids under the conditions studied.