Acute multifocal neuropathy following cocaine inhalation.

Introduction: We report a young man, not a habitual cocaine user, who developed an acute multifocal neuropathy following a second exposure to inhaled cocaine.

Methods: Case report.

Results: Clinical and electrophysiological findings suggested an acute multiple mononeuropathy following cocaine exposure.

Adult lead encephalopathy.

The neurotoxicity of lead to the adult brain is less well-known than that seen in children. It may present as acute severe encephalopathy or as chronic cognitive and behavioural symptoms, either in isolation or with systemic features of lead intoxication. Magnetic resonance imaging findings in lead encephalopathy vary.

Delayed chorea after recovery from a symmetric parkinsonian syndrome due to striatal myelinolysis.

Extrapontine myelinolysis (EPM) is rare and usually results from osmotic stress due to inappropriate correction of electrolyte disturbances. Parkinsonism is a relatively common manifestation of EPM, seen in 60% of patients. Dopaminergic therapy leads to good recovery in many patients.

More often striatal myelinolysis than pontine? A consecutive series of patients with osmotic demyelination syndrome.

Introduction: Osmotic demyelination syndrome (ODS) is increasingly recognized to involve extrapontine locations in addition to the better-known central pontine myelinolysis.

Aims: This study describes clinical and radiological features of consecutive patients with ODS detected over 1 year.

Methods: Patients fulfilling clinical and radiological criteria for ODS were prospectively enrolled and were followed with serial assessments during hospital stay and up to 253 days after discharge.