Publications by authors named "Parastoo Hassani-Abharian"
Background: Malaria parasites have gradually developed resistance to commonly used antimalarial drugs. For decades, chloroquine was the most widely used drug to eradicate malaria. However, with the spread of chloroquine resistance, many countries have adopted combination therapies that utilize two drugs acting synergistically instead of monotherapy.
View Article and Find Full Text PDFIran is one of the endemic regions of cutaneous leishmaniasis (CL) caused by . There is no protective vaccine available against CL available, and the most effective strategy is a definitive treatment. Topical medications can be an excellent option for this purpose.
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- Cutaneous leishmaniasis (CL) is a skin disease caused by certain Leishmania species, and this study examines the effectiveness of terpenoid-rich fractions from an herbal medicine against the promastigotes of these parasites.
- The research involved isolating six fractions using chromatography techniques, with fractions F4, F5, and F6 identified as having a high terpenoid content and being tested for their ability to kill leishmanial promastigotes at concentrations of 50 and 100 μg/ml over different incubation times.
- Results showed that higher concentrations and longer exposure times significantly reduced the viability of the parasites, with fraction F5 demonstrating the greatest leishmanicidal activity, indicating its potential for further
Article Synopsis
- * Researchers collected oral samples and confirmed yeast presence using specific culture methods and advanced identification techniques like PCR. Out of 93 isolates, a variety of species were identified, with a notable percentage showing multiple species in the same sample.
- * The findings indicate that drug use, particularly smoking certain substances, significantly impacts the types and frequency of Candida species in the oral cavities of addicts compared to healthy individuals.
Background And Purpose: is closely related to the most pathogenic and prevalent yeast, namely species can opportunistically overgrow in vulnerable individuals and cause a variety of diseases. The current study aimed to identify and isolate species present in the species complex identified in the oral cavity of drug abusers.
Materials And Methods: This study was conducted on 53 strains of species complex, isolated from the oral mucosa of drug abusers in Isfahan, Iran.