Enriched Environment Ameliorates Cognitive Deficits and Locomotor Sensitization in Morphine-Withdrawn Rats Receiving Methadone Maintenance Treatment.

Objective: This study was designed to examine whether enriched environments (EE) would attenuate object recognition and spatial learning and memory deficits and locomotor sensitization induced by methadone maintenance treatment (MMT) in morphine-withdrawn rats.

Methods: Male Wistar rats (170 ± 10 g) were injected with bi-daily doses (10 mg/kg, 12-h intervals) of morphine for 14 days. Rats receiving MMT were reared in the standard environment (SE) or EE during 30 days of morphine withdrawal.

Psychiatric disorders in children and adolescents: Prevalence and sociodemographic correlates in Semnan Province in Iran.

Aim: The aim of this study was to estimate the prevalence of psychiatric disorders and sociodemographic correlates in children and adolescents ages 6-18 years in semnan province.

Method: Participants were 1037 children and adolescents ages 6 to 18 years in Semnan. This study was a survey study and its data have been taken from the National survey of Iranian Children and Adolescents' Psychiatric Disorders in 2017.