Publications by authors named "Parasmal Suresh"
Article Synopsis
- - Mycobacterium marinum is a type of non-tuberculous mycobacterium commonly found in non-chlorinated water and is recognized as a pathogen for fish; in humans, it can cause skin infections and sometimes more serious conditions.
- - The text discusses four cases of cutaneous infections caused by M. marinum that were analyzed in a specialized medical center.
- - It emphasizes the importance of accurate diagnosis, the need for healthcare providers to maintain a high level of suspicion when encountering these infections, and reviews the treatment options available.
The rising prevalence of drug-resistant Mycobacterium tuberculosis (MTB) strains poses a significant challenge to global tuberculosis (TB) control efforts. This study aimed to analyze drug resistance patterns and investigate the molecular characteristics of 193 MTB clinical isolates to shed light on the mechanisms of drug resistance. Of the 193 MTB clinical isolates, 28.
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- * Of the culture-positive cases, 85.2% were identified as Mycobacterium tuberculosis, while 14.8% were classified as NTM, with dominant species including M. abscessus (33.3%) and M. fortuitum (24.6%).
- * The findings highlighted a low overall prevalence, but a high diversity of NTM species, emphasizing the need for precise identification of mycobacterial isolates for effective treatment options,
Eosinophilic meningitis caused by human diroflarial infection is rare. We report a case of eosinophilic meningitis and concomitant intraocular dirofilarial infection in India. Sequencing of the mitochondrial genome identified the worm as Dirofilaria sp.
View Article and Find Full Text PDFThe prevalence of human papillomavirus (HPV) types varies geographically between various countries and different parts of the same country. The efficacy of the HPV vaccines is dependent on the prevalent HPV types. Here, we have studied the prevalence of high-risk HPV (hrHPV) and its genotypes in women in our population.
View Article and Find Full Text PDFWe tried to determine the epidemiology and species of human dirofilariasis observed at two tertiary care hospitals in Kerala. We searched the hospital database to identify cases of dirofilariosis from January 2005 to March 2020. Along with human isolates, one dog Dirofilaria isolate was also subjected to PCR and sequencing of pan filarial primers cytochrome oxidase subunits 1 and 12S rDNA.
View Article and Find Full Text PDFIntroduction: We compared the hepatitis C virus (HCV) core antigen test with the HCV RNA assay to confirm anti-HCV results to determine whether the HCV core antigen test could be used as an alternative confirmatory test to the HCV RNA test.
Methods: Sera from 156 patients were analyzed for anti-HCV and HCV core antigen using a chemiluminescent microparticle immunoassay (Architect i2000SR) and for HCV RNA using the artus HCV RG RT-PCR Kit (QIAGEN) in a Rotor-Gene Q instrument.
Results: The diagnostic sensitivity, specificity, and positive and negative predictive values of the HCV core antigen assay compared to the HCV RNA test were 77.
BCG Infection due to MPT64-Negative Strain: A Diagnostic Challenge.
Am J Trop Med Hyg
September 2020
MPT64 is a 24-kDa immunogenic protein that is widely used as a diagnostic marker for the differentiation of complex (MTBC) from nontuberculous (NTM). Unlike , Bacillus Calmette-Guerin (BCG) vaccine strains with RD2 deletion do not secrete MPT64. Culture isolates from infections due to these strains may be falsely identified as nontuberculous in the absence of clinical correlation.
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