Publications by authors named "Paraskevi Papadogeorgou"
Article Synopsis
- Congenital heart disease (CHD) in neonates is linked to coagulation issues that increase morbidity and mortality, with a diverse population making consistent hemostatic patterns hard to identify.
- A study compared hemostatic profiles of 20 neonates with CHD to 18 healthy controls, revealing prolonged prothrombin time and decreased Factor VII in the CHD group, while Factors VIII, von Willebrand factor, and ristocetin cofactor activity were elevated.
- Though ADAMTS-13 levels were lower in CHD patients, this difference wasn't statistically significant, suggesting that while there is a moderately impaired coagulation profile, there's notable variability and heightened thrombogenicity in infants with CHD that needs to be addressed.
Neonatal sepsis is a life-threatening condition associated with significant morbidity and mortality. Sepsis-induced coagulopathy is a well-recognized entity, signifying the strong cross-talk between inflammation and coagulation. The aim of the present study was to compare the coagulation profile between the acute phase of sepsis and recovery in term and preterm neonates.
View Article and Find Full Text PDFKawasaki disease (KD) is an acute systemic vasculitis of childhood. The diagnosis is based on clinical criteria. However, the presentation of KD is incomplete/atypical for approximately 20 % of patients.
View Article and Find Full Text PDFChylomicron retention disease: report of two cases from a Greek Island.
J Pediatr Endocrinol Metab
March 2013
Chylomicron retention disease (CRD), or Anderson disease, is a rare, hereditary cause of fat malabsorption. It is one of the familial hypocholesterolaemia syndromes, along with homozygous hypobetalipoproteinaemia (HBL) and abetalipoproteinaemia (ABL). We report clinical, laboratory and histological data as well as molecular DNA analysis in the case of a 4-month-old boy with failure to thrive and steatorrhea who was diagnosed with CRD.
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