Publications by authors named "Paramonova T"

Due to the need to achieve the principles of sustainable development and to understand the processes of formation of phytocenoses in areas that were adversely affected by the industrial impact, this study assessed the condition of the Grachevsky uranium mine (Kazakhstan), which underwent conservation procedures about 25 years ago. The purpose is to determine the level of water quality and phytocenosis of the shores of the reservoir accumulating natural effluents from reclaimed dumps and anthropogenic sites of a uranium mine, as well as quality indicators and toxicology. The assessment included a qualitative research method (analysis of documents) to determine agro-climatic conditions and empirical methods of collecting information.

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To elucidate the features of bioaccumulation and phytotoxic effects of long-lived artificial radionuclides, a hydroponic experiment was carried out with the cultivation of onion (Allium cepa L.) in low-mineralized solutions spiked with Cs (250 kBq L) or Am (9 kBq L). After the 27-day growth period, ≈70% of Cs and ≈14% of Am were transferred from the solutions to onion biomass with transfer factor values ≈ 400 and ≈ 80, respectively.

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We report a case of a 4-month-old infant with dextro (d)-transposition of the great arteries, ventricular septal defect (VSD) and left ventricular outflow tract obstruction previously palliated with a systemic-to-pulmonary shunt. He underwent repair by aortic root translocation with an arterial switch procedure and coronary artery reimplantation (modified Bex-Nikaidoh operation). This case demonstrates that aortic translocation results in a more normal anatomic repair compared with the Rastelli operation.

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The article discusses treatment of 30 patients with chronic duodenal obstruction by means of an operation for duodenojejunostomy. Three variants of subcolonic duodenojejunostomy were used. The best drainage function of longitudinal duodenojejunostomy is noted.

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Autoradiography (3H-thymidine) and DNA-cytofluorometry were used to study the effect of quinoline dibromide (QD), a potential inhibitor of cobalamine-dependent methionine synthetase, on the kinetics of cell proliferation of L-1210 mouse leukemia. QD was found to produce the secondary blockade of leukemic cells in the late S-phase of the mitotic cycle. Such a mechanism of QD action promoted the potentiation of antitumor activity of the antimetabolites methotrexate, cytosine arabinoside and 5-fluorouracil during combined chemotherapy.

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