Publications by authors named "Parameswari Sabaratnam"
Neoscytalidium dimidiatum is an opportunistic fungus causing cutaneous infections mostly, which are difficult to treat due to antifungal resistance. In Malaysia, N. dimidiatum is associated with skin and nail infections, especially in the elderly.
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- Candida wangnamkhiaoensis is a newly identified species within the Hyphopichia clade, previously not found in clinical settings.
- This report marks the first association of C. wangnamkhiaoensis with fungaemia in an immunocompromised pediatric patient, identified as strain UZ1679/14 through PCR-sequencing methods.
- The isolate demonstrated sensitivity to multiple antifungal medications, and the patient showed clinical improvement after treatment with caspofungin.
Article Synopsis
- * Fereydounia khargensis, a yeast first identified in 2014, has now been associated with human infections for the first time.
- * Two cases involved HIV-positive and chronic renal failure patients, with the yeast showing multi-drug resistance to antifungal treatments.
Trichosporon species are opportunistic yeasts which can cause infections, especially in immunocompromised patients. This is a report of Trichosporon ovoides that caused subcutaneous infection in a patient with underlying ischemic heart disease. The identification of fungal isolate was confirmed by PCR sequencing of ITS and large subunit regions in rRNA gene.
View Article and Find Full Text PDFAn 11-year-old girl presented with multiple blisters on her the right foot complicated with cellulitis. The conventional and molecular identification were performed on the culture. The internal transcribed spacer (ITS) region in rRNA gene of the isolate was amplified by PCR.
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- A 61-year-old kidney transplant patient was found to have Prototheca wickerhamii in their blood, highlighting the organism's association with an uncommon disease called protothecosis, which is categorized under mycoses due to its clinical similarities to fungal infections.
- The appearance of P. wickerhamii colonies is similar to other yeast-like organisms, but can be accurately identified using commercial yeast identification systems, with electron microscopy revealing a distinctive "morula" structure.
- Although protothecosis is rare, especially in humans, it poses a risk as an opportunistic infection in immunosuppressed individuals, making this case notable as the first documented instance of disseminated algaemia caused by P. wickerham