[Medico-genetic studies of the Kostroma oblast population. X. Load of hereditary diseases in the population of Kostroma].

Medical-genetic study of the population of Kostroma (the total size of the population analysed approx. 250,000) was carried on. The load of hereditary diseases in the population (per 1000) was 0.

[Medico-genetic study of the Kostroma Region population. IX. Interpretation of the genetic distance matrix].

Two kinds of matrices of genetic distances were compared. The first originate from the distribution of surnames frequencies in communities of some districts of Kostroma province. The others were constructed, based on the population size and the physical distances between populations.

[Medico-genetic study of the Kostroma Region population. VIII. Genetic structure of large subdivided populations and its relation with the incidence of autosomal-recessive pathology].

FST was estimated for 67 communities and 6 small towns of Kostroma province. The mean FST value for rural and urban populations was (0.83 +/- 0.

[Medico-genetic study of the population of Kostroma Province. VI. The parameters of isolation by distance in the populations of the Bui and Shar'ya Districts of Kostroma Province].

A model of isolation by distance proposed by Malécot and developed by Morton is applied to the data on marriage distances collected in two regions of Kostroma Province. There is good agreement between the estimates of local inbreeding when using the isonymy method and the model of isolation by distance. Interpopulation kinship approaches 0 at the distance 700 km.

[The structure of the inbreeding coefficient in a rural Asian population].

The population-genetic study of an elementary rural population located in the Urgut district of Samarcand province was carried out. The pedigree for the whole population starting from the founders was evaluated. From 208 marriages presented in the population, 148 (71.

[Medico-genetic study of the population of the Kostroma region. III. Inbreeding coefficient and its dynamics in rural populations and small towns].

Analysis of the inbreeding coefficient, its structure and dynamics in rural and urbanized populations of the Kostroma province was performed. The coefficient of inbreeding was estimated for the "old" and "new" villages via migration and isonymy, the values being 0.001185; 0.

[Suitability of Russian surnames as a "quasi-genetic" marker].

The possible usefulness of Russian surnames as a quasi-genetic marker in the population study is analysed. Two approaches for the populations of different hierarchical levels are used. The coefficients of correlations between the matrices of genetical (based on gene frequencies in the populations) and quasi-genetical (based on surnames frequencies in the populations) distances were determined.