On the correction factors for small field dosimetry in 1.5T MR-linacs.

. Clinical dosimetry in the presence of a 1.5 T magnetic field is challenging, let alone in case small fields are involved.

Differences in landing biomechanics in the presence of delayed onset muscle soreness following or not active recovery.

Objective: Delayed onset muscle soreness (DOMS) can reduce joint range of motion and strength, cause edema, and increase joint stiffness. Here we set out to determine whether quadriceps DOMS followed by an active recovery low-intensity exercise alters jump landing biomechanics.

Methods: 3D landing kinematics, kinetics, and DOMS were evaluated in 26 healthy adults (15 women) performing drop and vertical jump landings before and after a squat protocol to induce quadriceps DOMS.

Contact with nature, nature prescriptions, and loneliness: Evidence from an international survey of adults in Australia, India, Singapore, the United Kingdom, and the United States.

Evidence to support nature contact and nature prescriptions to reduce loneliness is scant. A total of 2100 individuals took part in a survey conducted in Australia (n = 525, mean age = 34.1), India (n = 526, mean age = 29.

Validity of an Inertial Measurement Unit System to Measure Lower Limb Kinematics at Point of Contact during Incremental High-Speed Running.

There is limited validation for portable methods in evaluating high-speed running biomechanics, with inertial measurement unit (IMU) systems commonly used as wearables for this purpose. This study aimed to evaluate the validity of an IMU system in high-speed running compared to a 3D motion analysis system (MAS). One runner performed incremental treadmill running, from 12 to 18 km/h, on two separate days.

Relative profile measurements in 1.5T MR-linacs: investigation of central axis deviations.

. In 1.5 T MR-linacs, the absorbed dose central axis (CAX) deviates from the beam's CAX due to inherent profile asymmetry.

The Mitochondrial-Derived Peptide MOTS-c May Refine Mortality and Cardiovascular Risk Prediction in Chronic Hemodialysis Patients: A Multicenter Cohort Study.

Introduction: Uremic patients exhibit remarkably increased rates of mortality and cardiovascular (CV) events, but risk prediction in this setting remains difficult. Systemic mitochondrial dysfunction is pervasive in end-stage kidney disease and may contribute to CV complications. We tested the clinical significance of circulating MOTS-c, a small mitochondrial-derived peptide, as a biomarker for improving mortality and CV risk prediction in hemodialysis (HD) patients.

Unbalanced circulating Humanin levels and cardiovascular risk in chronic hemodialysis patients: a pilot, prospective study.

Background: Mortality and cardiovascular (CV) risk prediction in individuals with end-stage kidney disease (ESKD) on chronic hemodialysis (HD) remains challenging due to the multitude of implicated factors. In a multicenter ESKD-HD cohort, we tested the prognostic yield of the assessment of circulating Humanin, a small mitochondrial-derived peptide involved in CV protection, on CV events and mortality.

Methods: We conducted a prospective, observational, pilot study on 94 prevalent HD patients.

The economics of a national anterior cruciate ligament injury prevention program for amateur football players: a Markov model analysis.

Objectives: To estimate the long term cost savings, return on investment, and gain in quality-adjusted life years (QALYs) that could be achieved by a national anterior cruciate ligament (ACL) injury prevention program for amateur football (soccer) players in Australia.

Study Design: Markov model decision analysis.

Setting, Participants: Two hypothetical scenarios including all amateur football players in Australia (340 253 players): no intervention, and a national ACL injury prevention program.

Work-Related Musculoskeletal Disorders in Endoscopic Sinus and Skull Base Surgery: A Systematic Review With Meta-analysis.

Objective: Endoscopic sinus and skull base surgery has led to significant improvements in patient outcomes, yet may have come at a cost to surgeons' musculoskeletal (MSK) health. We aimed to determine the prevalence and characteristics of work-related MSK disorders (WRMDs) in endoscopic sinus and skull base surgeons; to investigate contributing factors for WRMD in this population; and to evaluate the effectiveness of ergonomic interventions on the severity or prevalence of WRMD in this population.

Data Sources: Medline, Embase, CINAHL, Web of Science, and Scopus from inception to April 2, 2024.

Global prevalence of musculoskeletal pain in rural and urban populations. A systematic review with meta-analysis. Musculoskeletal pain in rural and urban populations.

Introduction: To systematically compare the global prevalence of musculoskeletal pain and care-seeking in rural and urban populations.

Methods: A systematic review with meta-analysis of observational studies reporting a direct comparison of rural and urban populations was conducted worldwide and included back, knee, hip, shoulder, neck pain and a broad diagnosis of 'musculoskeletal pain'. A search strategy combining terms related to 'prevalence', 'musculoskeletal pain' and 'rural' was used on the following databases: MEDLINE, Embase, CINAHL, Scopus, and rural and remote health from their inception to 1 June 2022.

Development of a patient decision aid for children and adolescents following anterior cruciate ligament rupture: an international mixed-methods study.

Aim: To develop and user test an evidence-based patient decision aid for children and adolescents who are considering anterior cruciate ligament (ACL) reconstruction.

Design: Mixed-methods study describing the development of a patient decision aid.

Setting: A draft decision aid was developed by a multidisciplinary steering group (including various types of health professionals and researchers, and consumers) informed by the best available evidence and existing patient decision aids.

The effect of the KNEE program for Netball players on the modified Star Excursion Balance Test - a randomized controlled trial.

Background: The aim was to investigate the effect of the KNEE program on postural control as measured by the modified Star Excursion Balance test (mSEBT) in Australian club level netball players.

Methods: Two netball teams from Netball NSW Premier-League were recruited and randomized to complete either the KNEE program or a traditional warm-up. Cumulative, anterior, posteromedial, and posterolateral directions of the mSEBT were measured for both limbs at baseline, 8-weeks, and 5-months.

Ultraviolet Excitation of M-O (M = Phenalenone, Fluorenone, Pyridine, & Acridine) Complexes Resulting in O.

In our experiment, a trace amount of an organic molecule (M = 1-phenalen-1-one, 9-fluorenone, pyridine, or acridine) was seeded into a gas mix consisting of 3% O with a rare gas buffer (He or Ar) and then supersonically expanded. We excited the resulting molecular beam with ultraviolet light at either 355 nm (1-phenalen-1-one, 9-fluorenone, or acridine) or 266 nm (pyridine) and used resonance enhanced multiphoton ionization (REMPI) spectroscopy to probe for the formation of O in the a-Δ state, O. For all systems, the REMPI spectra demonstrate that ultraviolet excitation results in the formation of O and the oxygen product is confirmed to be in the ground vibrational state and with an effective rotational temperature below 80 K.

Validation of complex radiotherapy techniques using polymer gel dosimetry.

Modern radiotherapy delivers highly conformal dose distributions to irregularly shaped target volumes while sparing the surrounding normal tissue. Due to the complex planning and delivery techniques, dose verification and validation of the whole treatment workflow by end-to-end tests became much more important and polymer gel dosimeters are one of the few possibilities to capture the delivered dose distribution in 3D. The basic principles and formulations of gel dosimetry and its evaluation methods are described and the available studies validating device-specific geometrical parameters as well as the dose delivery by advanced radiotherapy techniques, such as 3D-CRT/IMRT and stereotactic radiosurgery treatments, the treatment of moving targets, online-adaptive magnetic resonance-guided radiotherapy as well as proton and ion beam treatments, are reviewed.

Don't Just Stand There. Rethinking the Ideal Body Posture for Otorhinolaryngologists.

Surgeons have a high rate of work-related musculoskeletal injuries; an area that has received little attention. These injuries result in surgeons performing less efficiently, needing to take time off work, suffering higher rates of burnout, and may ultimately lead surgeons to retire earlier than planned. Otorhinolaryngologists are at particular risk for work-related musculoskeletal injuries.

Circulating miRNA 122-5p Expression Predicts Mortality and Cardiovascular Events in Chronic Hemodialysis Patients: A Multicentric, Pilot, Prospective Study.

Background: Despite patients undergoing chronic hemodialysis (HD) being notoriously prone to adverse cardiovascular (CV) events, risk prediction in this population remains challenging. miRNA 122-5p, a short, non-coding RNA predominantly involved in lipid and carbohydrate metabolism, has recently been related to the onset and progression of CV disease.

Methods: We run a pilot, multicenter, longitudinal, observational study to evaluate the clinical significance and prognostic usefulness of circulating miRNA 122-5p in a multicentric cohort of 74 individuals on maintenance HD.

Who crashes their car following wrist fracture?

Background: Wrist fractures are common injuries associated with high disability in the early recovery period. The impact of wrist fractures on safe return to drive is not understood.

Purpose: (1) To compare the proportion of adults who were drivers in car crashes before and after wrist fracture; (2) To examine potential factors (demographic and/or clinical) associated with increased odds of being a driver in a car crash following wrist fracture.

Dose-response dependencies of OSL dosimeters in conventional linacs and 1.5T MR-linacs: an experimental and Monte Carlo study.

. This work focuses on the optically stimulated luminescence dosimetry (OSLD) dose-response characterization, with emphasis on 1.5T MR-Linacs.

Characterizing the origin band spectrum of isoquinoline with resonance enhanced multiphoton ionization and electronic structure calculations.

We report the experimental resonance enhanced multiphoton ionization spectrum of isoquinoline between 315 and 310 nm, along with correlated electronic structure calculations on the ground and excited states of this species. This spectral region spans the origin transitions to a π-π* excited state, which previous work has suggested to be vibronically coupled with a lower lying singlet n-π* state. Our computational results corroborate previous density functional theory calculations that predict the vertical excitation energy for the n-π* state to be higher than the π-π* state; however, we find an increase in the C-N-C angle brings the n-π* state below the energy of the π-π* state.

Financial burden of anterior cruciate ligament reconstructions in football (soccer) players: an Australian cost of injury study.

Objectives: To estimate the financial burden of anterior cruciate ligament (ACL) reconstructions in amateur football (soccer) players in Australia over a single year, including both direct and indirect cost.

Methods: Available national direct and indirect cost data were applied to the annual incidence of ACL reconstructions in Australia. Age-adjusted and sex-adjusted total and mean costs (ACL and osteoarthritis (OA)) were calculated for amateur football (soccer) players in Australia using an incidence-based approach.

Insurance cost and injury characteristics of anterior cruciate ligament injuries in sub-elite football: A population analysis involving 3 years of Australian insurance data.

Objectives: To investigate the injury characteristics and insurance cost of anterior cruciate ligament injuries in sub-elite football players in New South Wales, Australia.

Design: Descriptive epidemiological study.

Methods: Three years of insurance records (2018-2020) was used to describe anterior cruciate ligament injury costs and characteristics.

Heading in Football: insights from stakeholders in amateur football.

Despite emerging research questioning the long-term effect of purposeful heading on players' brain health, heading-related perspectives and behaviours of stakeholders in amateur football in Australia (a country without heading guidelines) remain unknown. This study aimed to explore the current heading-related perspectives and behaviours of football stakeholders. In total, 290 players (aged over 11 years), 54 coaches, 34 non-coaching staff and 14 medical staff completed the survey.

Singlet O from Ultraviolet Excitation of the Quinoline-O Complex.

We report results from experiments with the quinoline-O complex, which was photodissociated using light near 312 nm. Photodissociation resulted in formation of the lowest excited state of oxygen, O a Δ, which we detected using resonance enhanced multiphoton ionization and velocity map ion imaging. The O ion image allowed for a determination of the center-of-mass translational energy distribution, (), following complex dissociation.

Effects of an online program including mindfulness, exercise therapy and patient education compared to online exercise therapy and patient education for people with Patellofemoral Pain: protocol for a randomized clinical trial.

Background: Patellofemoral pain (PFP) is a common knee disorder that causes persistent pain, lower self-reported function and quality of life. People with PFP also present with altered psychological factors, which are associated with higher levels of pain and dysfunction. Mindfulness-based interventions (MBI) generally consist of meditative practices developed to provide a holistic approach to chronic conditions.