Publications by authors named "Papatsoris A"
Introduction: A model to predict the risk of surgical complications following percutaneous nephrolithotomy (PCNL) could be a useful tool to guide clinical decision-making. The aim of this study was to develop a simple and widely applicable stratification tool to be used for patient counseling, surgical planning, evaluation of outcomes, and academic reporting.
Methods: Data of patients who underwent PCNL were retrieved from the database of the collaborating centers including demographics of patients, characteristics of their stones and urinary tracts, and perioperative data.
Article Synopsis
- The COVID-19 pandemic has negatively impacted the mental health and treatment engagement of patients, leading to significant declines in voluntary attendance at psychiatric services.
- A study in Corfu, Greece, analyzed psychiatric ward attendance and admissions over a 12-month period post-pandemic compared to pre-pandemic data, revealing a 26.5% drop in voluntary patient attendance.
- Additionally, while the length of hospital stays increased by 13.2%, involuntary commitments and overall admission rates remained stable, highlighting differentiated effects on various psychiatric diagnoses.
Relugolix for the treatment of prostate cancer.
Expert Opin Pharmacother
December 2024
Introduction: Androgen deprivation therapy consists of the cornerstone of prostate cancer medical treatment. Until recently, castration of hypothalamus-hypophysis-gonadal axial was based on injectable medical agents. A few years ago, a novel per os administered GnRH antagonist was approved leading testosterone to castration level.
View Article and Find Full Text PDFThere has been a growing need for enhancements in healthcare delivery, especially for the improvement of surgical outcomes. Therefore, implementing consistent reporting of complications enables the evaluation of data quality and facilitates its comparison. There are currently many available reporting and grading systems each with its own set of benefits and drawbacks.
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- - Over the last 30 years, miniaturized percutaneous nephrolithotomy (mPCNL) has gained popularity due to its potential to reduce complications compared to standard procedures, but there's still debate over best practices and management strategies that hinders wider use.
- - An international panel of urology experts developed a consensus document on mPCNL to provide a comprehensive framework for practice, which included reviewing literature, identifying research gaps, and conducting surveys to gather expert opinions.
- - The study revealed 58 key questions on mPCNL practices, and consensus was achieved on 30 questions, affirming mPCNL as an effective technique for treating upper urinary tract stones in both adults and children.
PSMA-based therapeutics for prostate cancer.
Expert Opin Pharmacother
July 2024
Introduction: The prostate cancer (PCa) consists the most frequently diagnosed malignancy of urogenital system in males. Traditionally, treatment of localized PCa was based on surgery or radiotherapy while hormonotherapy was used in more advanced stages. However, the implementation of radiolabels has revolutionized the landscape of prostate cancer.
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- Experts met to discuss the best ways to treat urinary stones at a conference in Spain in January 2024.
- For 1.5 cm kidney stones, two treatments called m-PCNL and RIRS work well, but m-PCNL is cheaper and quicker, while RIRS has fewer side effects.
- Doctors need to be careful with patients on certain medications, as some treatments might cause more bleeding, and they should also make sure to test for infections before and after surgery.
Introduction: Benign Prostate Hyperplasia (BPH) significantly impacts men's health and quality of life, with its prevalence rising with age. This review critically examines the cost-effectiveness of pharmacological interventions for BPH to optimize patient outcomes and healthcare resource utilization.
Areas Covered: This review explores the integration of cost-effectiveness analysis (CEA) into clinical practice, balancing clinical efficacy with economic efficiency in BPH management.
Article Synopsis
- This study looked at how a special dye called indocyanine green (ICG) helps during kidney surgery to make things safer and more effective.
- Researchers reviewed different studies to find out the best uses, how much of the dye to use, and its effects on surgery time and blood loss.
- The findings showed that using ICG can lower surgery time and help doctors see better, which helps keep the kidney working well afterward.
Article Synopsis
- The study aims to understand treatment plans for patients with BCG-unresponsive non-muscle invasive bladder cancer (NMIBC) and the therapeutic decisions during BCG shortages in Arab countries.
- An online survey was conducted targeting urologists, with 106 responding; 55% reported treating over 10 BCG-unresponsive patients in the last 6 months, with radical cystectomy being the most favored treatment method (50%).
- Despite the preference for radical cystectomy, one-third of urologists are starting to use intravesical chemotherapy as an alternative, highlighting a need for better guidance and supportive measures regarding treatment options amid BCG shortages.
Background: In urology, ureteral stents are used to treat obstructive diseases. Hematuria (54%), fever, discomfort, and lower urinary system symptoms are the predominant symptoms related to ureteral stent.
Aim: This article links stent symptoms to double-j width and length, as well as patient's height, weight, and body mass index (BMI).
Article Synopsis
- * The study looked at how factors like lifestyle, obesity, and genetics can affect pregnancy loss, and both moms and dads can play a role.
- * Although it's recognized that a man's health can affect pregnancy chances, there aren’t enough specific recommendations for doctors on how to help couples facing this problem.
Article Synopsis
- The study aims to gather laser lithotripsy settings from experts for different clinical situations and to identify ways to minimize complications.
- A survey was conducted among laser specialists, revealing that the majority use Holmium-YAG lasers, with variations in settings for specific scenarios like middle-ureteral, pelvic, and lower pole stones.
- Experts reported a general consensus on preferred techniques, with preventive measures like power limits and intermittent activation commonly employed to reduce thermal injury risks during procedures.
Article Synopsis
- Pigtail stents are often used in urology to fix blockages, but many patients report issues like pain and fever.* -
- The article reviews different types of these stents to see how their materials and sizes might affect the problems people have.* -
- While some studies suggest that different stent types can cause different issues, the evidence isn't very strong, so more research is needed.*
Purpose: To highlight and compare experts' laser settings during endoscopic laser treatment of upper tract urothelial carcinoma (UTUC), to identify measures to reduce complications, and to propose guidance for endourologists.
Methods: Following a focused literature search to identify relevant questions, a survey was sent to laser experts. We asked participants for typical settings during specific scenarios (ureteroscopy (URS), retrograde intrarenal surgery (RIRS), and percutaneous treatment).
An overview of hormonal directed pharmacotherapy for the treatment of prostate cancer.
Expert Opin Pharmacother
November 2023
Introduction: Prostate cancer is the most common malignancy in the male. Androgen-deprivation therapy (ADT) has been the mainstay in the treatment of metastatic prostate cancer however, due to the outgrowth of castration-resistant cell population the disease inevitably progresses to an aggressive, difficult to handle stage.
Areas Covered: We have reviewed the literature regarding hormonal-directed therapy prostate cancer.
The purpose of this article is to review the effects of different types of pharmacotherapy on symptoms that affect the quality of a patient's life after stent insertion. A thorough Medline/PubMed nonsystematic review was conducted from 1987 to January 2023, using the terms: "pigtail" OR "ureteral stents" AND "lower urinary tracts symptoms" OR "LUTS" AND "pharmacotherapy" OR "drugs". Relevant studies conducted in humans and reported in English language were included.
View Article and Find Full Text PDFAcceptance of Artificial Intelligence in Supporting Cancer Patients.
Stud Health Technol Inform
June 2023
ASCAPE Project is a study aiming to implement the advances of Artificial Intelligence (AI), to support prostate cancer survivors, regarding quality of life issues. The aim of the study is to determine characteristics of patients who accepted to join ASCAPE project. It results that participants of the study mainly originate from higher-educated societies that are better informed about the potential benefits of AI in medicine.
View Article and Find Full Text PDFOn February 6, 2018, the European Atomic Energy Community reduced the annual equivalent dose limit for the lens from 150 to 20 mSv/year, because of its association with cataracts at low radiation doses. Our aim was to estimate the radiation doses received by the lens during endourologic procedures that require fluoroscopy. Multicenter study including prospective data of annual eye dosimeters between 2017 and 2020.
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- The study investigates the link between body weight and bladder cancer incidence in a Greek population, amidst established risk factors like smoking and occupational exposure.
- Results show that bladder cancer patients weighed more and had higher BMI and waist circumference compared to controls, but age, non-smoking status, and exposure to specific occupations remained the strong predictors of bladder cancer.
- The research indicates that while there is a potential weak association between increased body size and bladder cancer, it appears to be overshadowed by more significant risk factors in this population.
Introduction: This study aims to determine the effects of radical retropubic prostatectomy on post-operative erectile function.
Materials & Methods: A total of 50 patients were included in this study, diagnosed with localized prostate cancer, and underwent nerve-sparing radical retropubic prostatectomy. All patients completed the International Index of Erectile Function (IIEF-5) questionnaire pre-operatively and on the third, sixth, and twelfth post-operative month and completed a self-reporting of their satisfaction with their sexual performance.
The average age of fathers at first pregnancy has risen significantly over the last decade owing to various variables, including a longer life expectancy, more access to contraception, later marriage, and other factors. As has been proven in several studies, women over 35 years of age have an increased risk of infertility, pregnancy problems, spontaneous abortion, congenital malformations, and postnatal issues. There are varying opinions on whether a father's age affects the quality of his sperm or his ability to father a child.
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- The study investigates the clinical effects of PTEN loss and ERG rearrangement in localized prostate cancer patients post-radical prostatectomy.
- Data from 74 patients showed PTEN loss linked to higher cancer grades and a significant association with biochemical recurrence, while ERG rearrangement did not show a significant impact.
- The combination of PTEN loss and ERG rearrangement was more common in patients with higher cancer grades and recurrence, but this finding was not statistically significant.