Publications by authors named "Papasteriadi C"
Article Synopsis
- The study assesses factors affecting renal allograft survival, emphasizing the role of immunologic factors and the experience of a consistent surgical team.
- During a 22-year period, 575 renal transplant operations were analyzed, focusing on donor and recipient demographics, immunologic characteristics, and survival rates.
- Results indicate that donor age significantly impacts renal graft survival, while the presence of panel reactive antibodies post-transplantation has a notable effect on long-term outcomes, despite HLA mismatches showing no correlation with survival.
Deregulation of cell cycle and apoptosis pathways are known contributors to the pathogenesis of myelodysplastic syndromes (MDS). However, the underlying mechanisms are not fully clarified. The aim of our study was to examine mRNA expression levels of cell cycle and apoptosis regulatory genes, as well as the percentage of apoptotic and S phase cells and to correlate the findings with clinical characteristics and prognosis.
View Article and Find Full Text PDFThe aim of the present study was to examine caspases, granzyme B and bcl-2 family mRNA expression and the degree of apoptosis in the bone marrow (BM) of 46 Myelodysplastic Syndromes (MDS) and to correlate our findings with clinical parameters. The degree of apoptosis was determined by Annexin V, whereas expression of genes was determined using a multiprobe RNase Protection System. A positive correlation was found between caspases 8, 5, 3, 2, 1 and the level of apoptosis.
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