Quaternary E-W Extension Uplifts Kythira Island and Segments the Hellenic Arc.

Several crustal and lithospheric mechanisms lead to deformation and vertical motion of the upper plate during subduction, but their relative contribution is often enigmatic. Multiple areas of the Hellenic Forearc have been uplifting since Plio-Quaternary times, yet spatiotemporal characteristics and sources of this uplift are poorly resolved. The remarkable geology and geomorphology of Kythira Island, in the southwestern Hellenic forearc, allow for a detailed tectonic reconstruction since the Late Miocene.

Protein and mRNA Expression Levels of Interleukin-17A, -17F and -22 in Blood and Skin Samples of Patients with Mycosis Fungoides.

This study investigated the expression of interleukin (IL)-17A, -17F and -22 in mycosis fungoides. Blood samples were collected from 50 patients with mycosis fungoides and 50 healthy controls. Skin samples were obtained from 26 patients with mycosis fungoides and 5 healthy controls.

Planning considerations for a Mars Sample Receiving Facility: summary and interpretation of three design studies.

It has been widely understood for many years that an essential component of a Mars Sample Return mission is a Sample Receiving Facility (SRF). The purpose of such a facility would be to take delivery of the flight hardware that lands on Earth, open the spacecraft and extract the sample container and samples, and conduct an agreed-upon test protocol, while ensuring strict containment and contamination control of the samples while in the SRF. Any samples that are found to be non-hazardous (or are rendered non-hazardous by sterilization) would then be transferred to long-term curation.

Mineralogy and petrology of comet 81P/Wild 2 nucleus samples.

The bulk of the comet 81P/Wild 2 (hereafter Wild 2) samples returned to Earth by the Stardust spacecraft appear to be weakly constructed mixtures of nanometer-scale grains, with occasional much larger (over 1 micrometer) ferromagnesian silicates, Fe-Ni sulfides, Fe-Ni metal, and accessory phases. The very wide range of olivine and low-Ca pyroxene compositions in comet Wild 2 requires a wide range of formation conditions, probably reflecting very different formation locations in the protoplanetary disk. The restricted compositional ranges of Fe-Ni sulfides, the wide range for silicates, and the absence of hydrous phases indicate that comet Wild 2 experienced little or no aqueous alteration.

Elemental compositions of comet 81P/Wild 2 samples collected by Stardust.

We measured the elemental compositions of material from 23 particles in aerogel and from residue in seven craters in aluminum foil that was collected during passage of the Stardust spacecraft through the coma of comet 81P/Wild 2. These particles are chemically heterogeneous at the largest size scale analyzed ( approximately 180 ng). The mean elemental composition of this Wild 2 material is consistent with the CI meteorite composition, which is thought to represent the bulk composition of the solar system, for the elements Mg, Si, Mn, Fe, and Ni to 35%, and for Ca and Ti to 60%.

Isotopic compositions of cometary matter returned by Stardust.

Hydrogen, carbon, nitrogen, and oxygen isotopic compositions are heterogeneous among comet 81P/Wild 2 particle fragments; however, extreme isotopic anomalies are rare, indicating that the comet is not a pristine aggregate of presolar materials. Nonterrestrial nitrogen and neon isotope ratios suggest that indigenous organic matter and highly volatile materials were successfully collected. Except for a single (17)O-enriched circumstellar stardust grain, silicate and oxide minerals have oxygen isotopic compositions consistent with solar system origin.

Organics captured from comet 81P/Wild 2 by the Stardust spacecraft.

Organics found in comet 81P/Wild 2 samples show a heterogeneous and unequilibrated distribution in abundance and composition. Some organics are similar, but not identical, to those in interplanetary dust particles and carbonaceous meteorites. A class of aromatic-poor organic material is also present.

Growth inhibition of breast cancer cell lines overexpressing Her2/neu by a novel internalized fully human Fab antibody fragment.

The Her2/neu oncogene is overexpressed in various human cancers of epithelial origin and is associated with increased metastatic potential and poor prognosis. Blocking the Her2/neu signalling has been the focus of most therapeutic approaches. In this paper, the Her2/neu extracellular domain expressed in soluble form in yeast Pichia pastoris was used in order to isolate a fully human Fab fragment from a combinatorial Fab phage display library, derived from invaded lymph nodes of a breast cancer patient.

Determination of iridium in natural waters by clean chemical extraction and negative thermal ionization mass spectrometry.

Methods for the precise, routine measurement of Ir in seawater, riverwater, and estuarine water using isotope dilution negative thermal ionization mass spectrometry (ID-NTIMS) have been developed. After equilibration with a (191)Ir-enriched spike, Ir is separated from solution by coprecipitation with ferric hydroxide, followed by anion exchange chromatography using a reductive elution technique. UV irradiation is employed for the decomposition of trace organics, which interfere with negative ion production.

Magnesium isotopic composition of interplanetary dust particles.

The magnesium isotopic composition of some extraterrestrial dust particles has been measured. The particles are believed to be samples of interplanetary dust, a significant fraction of which originated from the disaggregation of comets and may contain preserved isotopic anomalies. Improvements in mass spectrometric and sample preparation techniques have made it possible to measure the magnesium isotopic composition of the dust particles, which are typically 10 micrometers in size and contain on the order of 10(-10) gram of magnesium.

Spirometric values for normal adult males in Greece.

We have measured the vital capacity and forced expiratory volume in 1 second of 50 healthy men aged 20 to 25 and 50 aged 55 to 60 years in order to obtain normal values for reference use for pulmonary tests in Greece. We constructed tables of mean and 95% confidence limits for ages 20 to 70 and height 1·5 to 1·9 metres, assuming that these respiratory values vary linearly with age and height. The differences in our results from those obtained in the United States of America and in France show that misinterpretation of pulmonary function tests may result from inappropriate reference values.

Ages, irradiation history, and chemical composition of lunar rocks from the sea of tranquillity.

The (87)Rb-(87)Sr internal isochrons for five rocks yield an age of 3.65 +/-0.05 x 10(9) years which presumably dates the formation of the Sea of Tranquillity.