Publications by authors named "Paolo Serafino"

Article Synopsis
  • * The surgery was performed in a university hospital setting, where the patient had a history of ovarian surgery and was undergoing ovarian stimulation to retrieve eggs for potential future use.
  • * Results showed that the laparoscopic approach was successful, allowing oocytes to be harvested while safely removing the teratoma, with the patient remaining awake and comfortable throughout the procedure.
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Article Synopsis
  • A 35-year-old woman diagnosed with stage II vaginal squamous cell carcinoma opted for fertility preservation before starting chemoradiotherapy.
  • Due to anatomical challenges and cancer-related risks, traditional oocyte retrieval methods were not feasible; thus, a laparoscopic approach was chosen under spinal anesthesia.
  • The procedure successfully retrieved and cryopreserved eight mature oocytes, marking a significant advance in fertility preservation techniques for women with vaginal cancer.
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Article Synopsis
  • The case report describes a conservative laparoscopic approach to treat a 14-week interstitial pregnancy in a 32-year-old woman, who experienced moderate abdominal pain with no identifiable risk factors for ectopic pregnancy.
  • The procedure involved careful techniques to minimize bleeding, including injecting vasopressin, and ultimately required a cornual resection to completely remove the ectopic mass.
  • The surgery lasted 55 minutes with minimal blood loss, resulting in a successful outcome with no complications, and follow-up revealed a normal uterus and resolution of the pregnancy hormone levels.
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Background: Endometrial cancer (EC) is one of the most common gynecologic malignancy, mostly in postmenopausal women. The gold standard treatment for EC is surgery, but in the early stages, it is possible to opt for conservative treatment. In the last decade, different clinical and pathological markers have been studied to identify women who respond to conservative treatment.

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Borderline ovarian tumors (BOTs) account for approximately 15% of all epithelial ovarian cancers. In 80% of cases the diagnosis of BOTs is done at stage I and more than a third of BOTs occurs in women younger than 40 years of age wishing to preserve their childbearing potential; the issue of conservative surgical management (fertility-sparing treatment) is thus becoming of paramount importance. At early stages, the modalities of conservative treatment could range from mono-lateral cystectomy to bilateral salpingo-oophorectomy.

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The laparoscopic approach for the treatment of uterine leiomyoma is increasingly practiced. The necessity to remove large specimens from the small laparoscopic incision has always been one of the main limits of this procedure. The unrestricted use of morcellation, to overtake this weak point of minimally invasive surgery, has opened in recent years a broad debate, especially on the risk of unintended dissemination of cells that could in some cases lead to extremely negative repercussions.

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Study Objective: To describe the diagnostic workup and laparoscopic management of a noncommunicating left uterine rudimentary horn (class U4aC0V0 European Society of Human Reproduction and Embryology/European Society of Gastrointestinal Endoscopy Classification) with communicating endometriotic bladder nodule.

Design: Step-by-step description of the surgical treatment.

Patient: A 33-year-old woman with unicornuate uterus and a left-side noncommunicating rudimentary horn affected by primary infertility, mild dysmenorrhea (visual analog scale score 6), severe catamenial dysuria (visual analog scale score 10), and catamenial hematuria.

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Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease. The hypothesis that alterations in the microbiome are involved in the genesis of PCOS has been postulated. Aim of this review is to summarize the available literature data about the relationship between microbiome and PCOS.

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