The Interplay between Histamine H Receptor and the Kidney Function: The Lesson from H Receptor Knockout Mice.

Previous studies implicated the histamine H receptor in renal pathophysiology. The aim here is to elucidate the role of this receptor on renal function using H receptor knockout mice (HR). Healthy and diabetic HR mice compared to their C57BL/6J wild-type counterpart for renal function and the expression of crucial tubular proteins.

Efficacy and safety of topical eprinomectin to control Myocoptes musculinus infestation in mice.

Myocoptes musculinus is the most common fur mite identified among laboratory mice; infested mice, in addition to dermatological signs, may also be prone to secondary infections, affecting the outcome of a research trial. This trial was conducted in order to assess the safety and efficacy of a single topical administration of eprinomectin (5mg/kg BW) in a naturally infested laboratory mice colony. A safety trial was conducted on 20 uninfested pregnant females assigned to two groups, receiving eprinomectin and mineral oil, respectively.