Overdiagnosis in the era of neuropsychiatric imaging.

New guidelines proposed by the National Institute of Mental Health are intended to transform the management of patients with psychiatric disorders. It is anticipated that neuroimaging and other biomarkers will play a more prominent role in diagnosis and prognosis, especially in the prodromal phase of illness. Earlier treatment of psychiatric disorders has the potential to improve outcomes significantly.

Characteristics of spondylotic myelopathy on 3D driven-equilibrium fast spin echo and 2D fast spin echo magnetic resonance imaging: a retrospective cross-sectional study.

In patients with spinal stenosis, magnetic resonance imaging of the cervical spine can be improved by using 3D driven-equilibrium fast spin echo sequences to provide a high-resolution assessment of osseous and ligamentous structures. However, it is not yet clear whether 3D driven-equilibrium fast spin echo sequences adequately evaluate the spinal cord itself. As a result, they are generally supplemented by additional 2D fast spin echo sequences, adding time to the examination and potential discomfort to the patient.

Use of diffusion tensor imaging in glioma resection.

Diffusion tensor imaging (DTI) is increasingly used in the resection of both high- and low-grade gliomas. Whereas conventional MRI techniques provide only anatomical information, DTI offers data on CNS connectivity by enabling visualization of important white matter tracts in the brain. Importantly, DTI allows neurosurgeons to better guide their surgical approach and resection.

Automated diffusion tensor tractography: implementation and comparison to user-driven tractography.

Rationale And Objectives: Diffusion tensor tractography offers a unique perspective of white matter anatomy, but proper delineation of white matter tracts of interest generally requires the active involvement of an expert neuroanatomist. The investigators describe the implementation of an automated tractographic method requiring no user input and compare its results to those from user-driven tractography.

Materials And Methods: Fourteen healthy volunteers underwent diffusion tensor imaging at 3 T.

Diffusion-tensor MR imaging and tractography: exploring brain microstructure and connectivity.

Diffusion magnetic resonance (MR) imaging is evolving into a potent tool in the examination of the central nervous system. Although it is often used for the detection of acute ischemia, evaluation of directionality in a diffusion measurement can be useful in white matter, which demonstrates strong diffusion anisotropy. Techniques such as diffusion-tensor imaging offer a glimpse into brain microstructure at a scale that is not easily accessible with other modalities, in some cases improving the detection and characterization of white matter abnormalities.

Leftward asymmetry in relative fiber density of the arcuate fasciculus.

Left hemispheric language dominance is well established, but the structural substrate for this functional asymmetry is uncertain. We report a strong asymmetry in the relative fiber density of the arcuate fasciculus, a white matter pathway associated with language that connects the frontal, temporal, and parietal lobes. Measured with diffusion tensor tractography, nearly all study participants demonstrated greater relative fiber density in the left arcuate fasciculus than in the right arcuate fasciculus.