Publications by authors named "Paolo Cortese"

Article Synopsis
  • The Italian Ministry of Health implemented a COVID vaccination plan for frail patients and healthcare workers starting in January 2021, using a three-dose regimen.
  • A study involving 53 family pediatricians was conducted to assess immune responses post-vaccination through various laboratory techniques, revealing that while antibody levels rose significantly after the third dose, they did not predict infection risk.
  • The research found that after the booster, activated T cell responses, particularly CD8 IFN-γ levels, were significantly associated with a lower risk of infection in the following six months, highlighting potential implications for other vaccine strategies.
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Background And Aims: Aetiopathogenesis of chorioangioma is already unknown. Among the risk factors, hypoxia, environmental and genetic factors are believed to induce the overexpression of angiogenic cytokines promoting vascular proliferation. We reported a case of prenatally diagnosed 67 mm-wide placental chorioangioma, which occurred at 32 weeks of gestational age, infarcted, and followed by the onset of a second infarcted chorioangioma at 35 weeks of gestational age.

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Polyamidoamines (PAAs) are a well-known family of synthetic biocompatible and biodegradable polymers, which can be prepared as soft hydrogels characterized by low interfacial tension and tunable elasticity. For the first time we report here on the in vivo performance of a PAA hydrogel implant as scaffold for tissue engineering. In particular, an amphoteric agmatine-deriving PAA hydrogel shaped as small tubing was obtained by radical polymerization of a soluble functional oligomeric precursor and used as conduit for nerve regeneration in a rat sciatic nerve cut model.

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Objectives: To report intermediate-term results with reference to quality of life (QoL) and complications in 232 consecutive patients with stress urinary incontinence (SUI) treated with a transvaginal pubic bone-anchored sling (BAS).

Methods: We retrospectively reviewed 232 consecutive patients affected by SUI who underwent BAS using biologic and synthetic materials, with a mean follow-up of 50 months. Stress urinary incontinence was due to a defect of anatomic support and to intrinsic sphincteric deficiency in 220 patients and 12 patients, respectively.

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