Synopsis of recent research by authors named "Paolo Battuello"
- Paolo Battuello's recent research focuses on colorectal cancer (CRC), aiming to improve diagnosis and treatment through innovative methodologies, particularly in the analysis of cell-free DNA (cfDNA) and mutational signatures.
- His findings highlight the mechanisms of cfDNA release in cancer cells, emphasize the importance of standardizing mutational signature analyses, and demonstrate how temozolomide treatment can alter mismatch repair functions and increase mutational burden, thereby enhancing immunotherapy responsiveness.
- Additionally, Battuello advocates for integrated precision oncology approaches to address the unmet clinical needs of metastatic colorectal cancer, aiming to improve patient outcomes through tailored treatment strategies.
