Publications by authors named "Paola Saporita"
A review of scientific information about the potential role of medicinal mushrooms in the prevention and treatment of gynecological cancers, human immunodeficiency virus, and human papillomavirus infections is reported here. The results of in vivo and in vitro experiments on 16 different species of Basidiomycetes and three Ascomycetes, which possess chemopreventive potential and are effective in clinical application in combination with chemotherapy, are also discussed. Medicinal mushroom extracts confirm an evident efficacy on the reduction of tumor cell proliferation and side effects in patients with gynecological tumors who are undergoing chemotherapy treatments.
View Article and Find Full Text PDFStructural Characterization of Polysaccharides of a Productive Strain of the Culinary-Medicinal King Oyster Mushroom, Pleurotus eryngii (Agaricomycetes), from Italy.
Francesca Cateni Marina Zacchigna Celeste Caruso Bavisotto Giuseppe Procida Giuseppe Bonaventura Paola Saporita
Int J Med Mushrooms
January 2019
Article Synopsis
- A study on the strain C-142-c of the edible mushroom Pleurotus eryngii revealed that it has significant antioxidant activity due to two isolated polysaccharides, PEPS-A1 (α-glucan) and PEPS-A2 (β-glucan).
- The structures of these polysaccharides were determined using advanced techniques like nuclear magnetic resonance and methylation analysis, with PEPS-A1 having a repeating unit of α-D-Glcp and PEPS-A2 having a unit of β-D-Glcp.
- Both polysaccharides demonstrated the ability to scavenge hydroxyl radicals and showed potential antitumor effects, significantly reducing the viability of colorectal adenocarcinoma cells at specific concentrations,