From mitochondria to healthy aging: The role of branched-chain amino acids treatment: MATeR a randomized study.

Rationale: Malnutrition often affects elderly patients and significantly contributes to the reduction in healthy life expectancy, causing high morbidity and mortality. In particular, protein malnutrition is one of the determinants of frailty and sarcopenia in elderly people.

Methods: To investigate the role of amino acid supplementation in senior patients we performed an open-label randomized trial and administered a particular branched-chain amino acid enriched mixture (BCAAem) or provided diet advice in 155 elderly malnourished patients.

The association of indwelling urinary catheter with delirium in hospitalized patients and nursing home residents: an explorative analysis from the "Delirium Day 2015".

Backround: Use of indwelling urinary catheter (IUC) in older adults has negative consequences, including delirium.

Aim: This analysis, from the "Delirium Day 2015", a nationwide multicenter prevalence study, aim to evaluate the association of IUC with delirium in hospitalized and Nursing Homes (NHs) patients.

Methods: Patients underwent a comprehensive geriatric assessment, including the presence of IUC; inclusion criteria were age > 65 years, being Italian speaker and providing informed consent; exclusion criteria were coma, aphasia, end-of-life status.

Length of Stay in the Emergency Department and Occurrence of Delirium in Older Medical Patients.

Objectives: To determine whether emergency department (ED) length of stay before ward admission is associated with incident delirium in older adults.

Design: Prospective cohort study.

Setting: Hospital.