Publications by authors named "Paola Polistena"
Article Synopsis
- Obesity increases the risk of venous thromboembolism (VTE), and this study aimed to determine the best enoxaparin dosage for obese patients.
- The study included 47 obese patients and 20 non-obese controls, examining their clinical outcomes and the need for dosage adjustments based on anti-Xa levels.
- Results showed that BMI-stratified dosing of enoxaparin was safe and effective for treating VTE in obese patients, while prophylaxis with a specific dosage helped prevent VTE without significant bleeding risks.
Cytomegalovirus (CMV) infection causes morbidity and mortality after allogeneic haematopoietic stem cell transplantation (HSCT). We investigated whether prophylaxis with high dose valaciclovir is effective at reducing the incidence of clinically significant CMV infection (csCMVi) within six months of allogeneic HSCT. Consecutive allogeneic HSCT recipients who received 2g valaciclovir orally four times daily from transplant until day 100 (prophylaxis group) were compared to subsequent patients who received no CMV prophylaxis (control group).
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