Ocular Behçet's Disease: Changing Patterns Over Time, Complications and Long-Term Visual Prognosis.

Purpose: To investigate demographic, clinical features and complications of Italian patients with ocular Behçet's disease (BD) over time.

Methods: Retrospective study of 385 patients examined from 1968 to 2011, 265 of whom had follow-up ≥ 12 months.

Results: A significant increase in the proportion of females (p = 0.

Contact Lens Care among Teenage Students in Italy: A Cross-Sectional Study.

Aim: To assess the attitude and practice of contact lens (CL) wearers among teenage school students and to evaluate how much the teenagers adhere to the CL care procedures according to the proper care of CL guidelines.

Methods: A cross-sectional descriptive study of Italian teenagers from high schools in Rome who wear CL. We inquired about the different aspects of CL care through a questionnaire.

Juvenile idiopathic arthritis-associated uveitis at an Italian tertiary referral center: clinical features and complications.

Purpose: To describe the frequencies and risk factors of ocular complications and poor visual outcomes in children with juvenile idiopathic arthritis (JIA).

Methods: Retrospective cohort study, including 69 consecutive children (116 eyes) affected by JIA-associated uveitis managed at a tertiary uveitis clinic.

Results: The incidence of visual loss to the 20/50 or worse threshold was 0.

Intermediate uveitis: comparison between childhood-onset and adult-onset disease.

Purpose: To compare demographic and clinical data, systemic disease association, visual prognosis, and complications found in childhood and adult onset of intermediate uveitis (IU).

Methods: Retrospective cohort study of 287 patients with IU: 122 (42.5%) children at onset (<16 years), 165 (57.

Effects of intravitreal bevacizumab on inflammatory choroidal neovascular membrane.

purpose. To test the efficacy of intravitreal bevacizumab (IB) in the treatment of inflammatory choroidal neovascularization (CNV). 
Methods.

Intermediate uveitis in a pediatric Italian population.

Purpose: To investigate clinical data, outcome, and treatment of intermediate uveitis in children.

Methods: Retrospective cohort study, including 116 children affected by intermediate uveitis.

Results: Sixty-two percent of patients were males.

Role of the intravitreal growth factors in the pathogenesis of idiopathic epiretinal membrane.

Purpose: The aim of the present study is to evaluate the roles of TGFs β1 and β2, glial cell line-derived neurotrophic factor (GDNF), and nerve growth factor (NGF) in the pathogenesis of idiopathic epiretinal membrane (ERM).

Methods: Eight patients, six males and two females, with an average age of 60.25 ± 17.

Central serous chorioretinopathy as a presenting symptom of endogenous Cushing syndrome: a case report.

Purpose: To report a case of Cushing syndrome due to adrenocortical adenoma revealed by central serous chorioretinopathy.

Materials And Methods: A 45-year-old man presented with blurred vision and metamorphopsia in the left eye. He reported few episodes of high blood pressure in the last 3 months.

Retinal complications of juvenile idiopathic arthritis-related uveitis: a microperimetry and optical coherence tomography study.

Purpose: To evaluate ocular complications of juvenile idiopathic arthritis (JIA)-related uveitis; to study macular morphology and sensitivity.

Methods: Retrospective chart review of 67 patients. Fourteen consecutive patients (24 eyes) observed from January to December 2008 were submitted to optical coherence tomography study (OCT) and microperimetry MP-1 examination.

Bilateral uveitis with hypopyon as a presenting symptom of metastatic peritoneal carcinomatosis.

Purpose: To report the association between bilateral uveitis with hypopyon and metastatic peritoneal carcinomatosis.

Methods: A 76-year-old woman presented bilateral diffuse uveitis with hypopyon. She was in good health.

Progression of essential iris atrophy studied with confocal microscopy and ultrasound biomicroscopy: a 5-year case report.

Purpose: The purpose of this study was to report the progression of the iridocorneal endothelial syndrome during a 5-year period in a patient with the essential iris atrophy variant using confocal microscopy and ultrabiomicroscopy (UBM).

Methods: A 47-year-old woman was referred to us in January 2002 with suspected iridocorneal endothelial syndrome. Examination of both eyes included visual acuity, biomicroscopy, intraocular pressure measurement, gonioscopy, visual field test, and UBM.

Optical coherence tomography for classification and clinical evaluation of macular edema in patients with uveitis.

Purpose: To study use of optical coherence tomography (OCT) for macular edema in uveitis.

Methods: In total, 44 patients with uveitis and macular edema underwent OCT. Data obtained were correlated with anatomic type, duration of uveitis, and visual acuity (VA).

Infliximab treatment for ocular and extraocular manifestations of Behçet's disease.

Purpose: To assess the efficacy and safety of infliximab in the treatment of sight-threatening uveitis and extraocular manifestations in patients with Behçet's disease.

Methods: Twelve patients with Behçet's disease and uveitis were treated with infliximab after unsuccessful therapy with other immunosuppressive drugs. The main outcome measures were as follows: the number of uveitis relapses, the number of Behçet's disease-related extraocular lesions, and the amount of corticosteroids administered during the treatment as well as during an equal prior period of time while the patients were on other immunosuppressive agents.

Evaluation of the effect on outcomes of the route of administration of corticosteroids in acute Vogt-Koyanagi-Harada disease.

Purpose: To compare the effect on outcomes of the route of administration of corticosteroids in acute Vogt-Koyanagi-Harada disease.

Design: Retrospective comparative interventional case series.

Settings: Nine international uveitis specialty clinics.

Diffuse granulomatous necrotizing scleritis.

Case Report: A 34-year-old man presented with anterior scleral thinning in the right eye (RE) and a painful nodular scleritis in the left eye (LE). Fundus examination showed a healed vasculitis and an inferior epiretinal neovascular membrane in the LE. Topical and systemic oral steroids and antiviral medication were prescribed.

Vogt-Koyanagi-Harada syndrome and keratoconjunctivitis sicca.

Purpose: To discover a relationship between Vogt-Koyanagi-Harada (VKH) syndrome and Sjögren syndrome.

Design: Observational case-control study.

Methods: Sixteen Italian patients with VKH syndrome and 16 controls with diffuse uveitis underwent tear analysis and rheumatologic evaluation.

Paracentral corneal melting in a patient with Vogt-Koyanagi-Harada's syndrome, psoriasis, and Hashimoto's thyroiditis.

The paper describes the occurrence of unilateral paracentral corneal melting in a 65-year-old woman with ocular and systemic signs of Vogt-Koyanagi-Harada's syndrome (VKH), psoriasis, and Hashimoto's thyroiditis. Corneal melting, often occurring in association with systemic vasculitis and connective tissue diseases, has rarely been reported in relation to diffuse psoriasis and never in association with VKH. A possible relationship between corneal melting and VKH is suggested.

Uveitis in Turner's syndrome.

Background: Turner's syndrome is a chromosomal abnormality where phenotypic females have either a missing X chromosome or a structural aberration of the X chromosome. Several ocular diseases have been associated with Turner's syndrome in the past, including one case only of proven iridocyclitis.

Methods: In this study we report the clinical findings of three females with Turner's syndrome and uveitis followed up for a mean period of 12.