Publications by authors named "Paola Ortiz Gonzalez"
J Bone Miner Res
October 2024
Article Synopsis
- Vertebrate sexual dimorphism, traditionally linked to the type of gonads (testes or ovaries) and their hormone production, is now shown to also be influenced by sex chromosomes (XX or XY).
- Using the Four-Core Genotypes (FCG) mouse model, the study reveals that both gonads and sex chromosomes affect the musculoskeletal system's development, with notable differences becoming more pronounced in older mice.
- Findings indicate that while gonadal sex plays a significant role in musculoskeletal traits, sex chromosomes contribute meaningfully to differences in body composition and bone strength, particularly as the mice mature.
