Publications by authors named "Paola N Marques"

Article Synopsis
  • - The study aimed to investigate endoscopic and histopathological changes in the esophagus, stomach, and duodenum of Crohn's disease patients through esophagogastroduodenoscopies and biopsies, assessing bacterial presence with Giemsa staining.
  • - Out of 58 patients, significant findings included erosive esophagitis in 43.1%, gastritis in 55.2%, and erosive duodenitis in 13.8%, with varying inflammatory activity noted in patients with and without bacterial infection.
  • - The findings revealed a prevalence of nonspecific changes linked to Crohn's disease, with rare instances of focally enhanced gastritis, while factors like time since diagnosis, age, and ongoing treatments
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 A novel endoscopic optical diagnosis classification system (SIMPLE) has recently been developed. This study aimed to evaluate the SIMPLE classification in a clinical cohort.  All diminutive and small colorectal polyps found in a cohort of individuals undergoing screening, diagnostic, or surveillance colonoscopies underwent optical diagnosis using image-enhanced endoscopy (IEE) and the SIMPLE classification.

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Background: Standard colonoscopy practice requires removal and histological characterization of almost all detected small (< 10 mm) and diminutive (≤ 5 mm) colorectal polyps. This study aimed to test a simplified polyp-based resect and discard (PBRD) strategy that assigns surveillance intervals based only on size and number of small/diminutive polyps, without the need for pathology examination.

Methods: A post hoc analysis was performed on patients enrolled in a prospective study.

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