Publications by authors named "Paola Munoz"

Introduction: The incidence of squamous carcinoma of the oropharynx (OPSCC) has presented an increase worldwide, a fact that occurs along with a phenomenon of epidemiological transition, whose pathogenesis is linked to human papilloma virus (HPV) in a significant part of the cases. Published evidence at the Latin American level is scarce. The present study aims to evaluate the epidemiological and clinical characteristics of patients with oropharyngeal cancer treated in a public oncology reference centre in Chile.

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Background: Skeletal muscle injury characterisation during healing supports trauma prognosis. Given the potential interest of computed tomography (CT) in muscle diseases and lack of in vivo CT methodology to image skeletal muscle wound healing, we tracked skeletal muscle injury recovery using in vivo micro-CT in a rat model to obtain a predictive model.

Methods: Skeletal muscle injury was performed in 23 rats.

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Lithopedion ( = rock and  = child) is a rare condition that only occurs in 1.5 to 1.8% of extrauterine pregnancies and in 0.

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Late onset Alzheimer disease's (LOAD) main risk factor is aging. Although it is not well known which age-related factors are involved in its development, evidence points out to the involvement of an impaired amyloid-β (Aβ) clearance in the aged brain among possible causes. Glial cells are the main scavengers of the brain, where Scavenger Receptor class A (SR-A) emerges as a relevant player in AD because of its participation in Aβ uptake and in the modulation of glial cell inflammatory response.

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In recent decades, essential oils (EOs) have become an important alternative source of antimicrobial agents. The objective of this study was to evaluate the antimicrobial activity of EOs obtained from the leaves of Myrcianthes leucoxyla Mc. Vaughn.

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The activation of microglia has been recognized for over a century by their morphological changes. Long slender microglia acquire a short sturdy ramified shape when activated. During the past 20 years, microglia have been accepted as an essential cellular component for understanding the pathogenic mechanism of many brain diseases, including neurodegenerative diseases.

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The purpose of this research was to obtain information about general and pandemic preparedness efforts of residents within San Patricio County in South Texas, as well as to identify the most effective means of communicating the risks posed by pandemic influenza. The population of San Patricio County is socially vulnerable to a variety of disasters, including influenza pandemics due to the unique demographic profile of the county as well as its location on the Gulf Coast. The goals of this study were to help with pandemic planning efforts and to provide recommendations that could serve as a foundation for building more resilient communities within San Patricio County.

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Purpose: This aim of this study was to evaluate the effect of splinting mini-implants on marginal bone loss when used to retain mandibular overdentures.

Materials And Methods: With mathematical models, a finite element analysis was performed to compare the bone stress distribution around two mini-implants, either splinted with a bar superstructure or not splinted. In the clinical portion of this study, 90 mini-implants were placed in the anterior mandibles of 45 completely edentulous patients selected from a public health center.

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The prophylactic use of antibiotics when a hip replacement procedure is performed has been subject of intense debate. Prevention of such an infection is complex, with many unresolved issues that require considerable investigation. The attentive application of reasonable principles of infection control with the goals of optimization of the wound environment, augmentation of the host response, and minimization of bacterial contamination in the preoperative, and postoperative time-period is essential to that overall reduction of the frequency of infection.

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