Publications by authors named "Paola Melgar"

Textbook outcome (TO) is a composite measure that reflects the most desirable surgical results as a single indicator. The aim of this study was to assess the achievement of TO at a hepatopancreatobiliary (HPB) surgery unit in a Spanish tertiary hospital. We performed a retrospective observational study of all consecutive patients who underwent HPB surgery over a 4-year period.

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Article Synopsis
  • Breast cancer is prevalent among women, with 20-30% of patients developing metastases, primarily affecting the liver. Patients with liver metastases have a wide range of survival rates, influenced by various factors.
  • This study aimed to assess the long-term survival and disease-free outcomes for patients who had surgery for liver metastases stemming from breast cancer.
  • Results indicated that surgery can enhance long-term survival, with specific patient characteristics (like health status, hormone receptor positivity, and prior treatments) linked to improved outcomes.
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Background & Aims: Liver transplantation (LT) is one of the most complex surgical procedures. Enhanced recovery after surgery (ERAS) aims to reduce the risk of postoperative complications. When patients achieve all desirable outcomes after a procedure, they are considered to have experienced a textbook outcome (TO).

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Background: Enhanced Recovery After Surgery (ERAS) is a multimodal, evidence-based, program of care developed to minimize the response to surgical stress, associated with reduced perioperative morbidity and hospital stay. This study presents the specific ERAS Society recommendations for liver transplantation (LT) based on the best available evidence and on expert consensus.

Methods: PubMed and ClinicalTrials.

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Background & Aims: Few studies have fully applied an enhanced recovery after surgery (ERAS) protocol to liver transplantation (LT). Our aim was to assess the effects of a comprehensive ERAS protocol in our cohort of low- and medium-risk LT patients.

Methods: The ERAS protocol included pre-, intra-, and post-operative steps.

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Bacterial (bact)DNA is an immunogenic product that frequently translocates into the blood in cirrhosis. We evaluated bactDNA clearance in patients undergoing liver transplantation (LT) and its association with inflammation and clinically relevant complications. We prospectively included patients consecutively admitted for LT in a one-year follow-up study.

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